A three-dimensional model of the human airway tree
A three-dimensional model of the human airway tree
复制标题
DOI：
10.1152/jappl.1999.87.6.2207
复制
发表时间：
1999-12-01
影响因子：
3.3
通讯作者：
Suki, B
中科院分区：
文献类型：
--
作者：
Kitaoka, H;Takaki, R;Suki, B
提出了一种使用确定性算法的人体气道树的三维（3D）模型，该算法可以在器官中生成分支管道系统。该算法基于两个原理：1）通过分支输送的流体量与其供应的区域的体积成比例;以及2）末端分支均匀地布置在器官内。这些原则定义了分支的基本过程：两个子分支的维度和方向性的生成由父分支的属性和父分支提供的区域控制。该算法由9条基本规则和4条补充规则组成。当器官的轮廓和躯干的位置被指定时，分支被算法连续地生成。应用于人类肺部，该算法生成了一个由54，000个分支组成的气道树。其形态计量学特征与文献报道一致。该算法和三维气道模型可用于研究肺中的结构-功能关系。
A three-dimensional (3D) model of the human airway tree is proposed using a deterministic algorithm that can generate a branching duct system in an organ. The algorithm is based on two principles: 1) the amount of fluid delivery through a branch is proportional to the volume of the region it supplies; and 2) the terminal branches are arranged homogeneously within the organ. These principles define the basic process of branching: generation of the dimensions and directionality of two daughter branches is governed by the properties of the parent branch and the region the parent supplies. The algorithm is composed of nine basic rules and four complementary rules. When the contour of an organ and the position of the trunk are specified, branches are successively generated by the algorithm. Applied to the human lung, the algorithm generates an airway tree that consists of similar to 54,000 branches. Its morphometric characteristics are in good agreement with those reported in the literature. The algorithm and the 3D airway model are useful for studying the structure-function relationship in the lung.