Barostat or dynamic balloon distention test: which technique is best suited for esophageal sensory testing?

Barostat or dynamic balloon distention test: which technique is best suited for esophageal sensory testing?
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恒压器或动态球囊扩张测试:哪种技术最适合食管感觉测试?

DOI:
10.1111/j.1442-2050.2011.01294.x
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发表时间:
2012
期刊:
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
影响因子:
--
通讯作者:
Rao,SSC
Rao,SSC
中科院分区:
--
文献类型:
--
作者:
Remes-Troche,JM;Attaluri,A;Chahal,P;Rao,SSC

文献摘要

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食道感觉的评估通常采用恒压辅助球囊扩张(BBD)或动态球囊扩张(DBD)技术,但它们的相对优劣尚不清楚。我们的目的是比较两种技术的实用性和耐受性。16名健康志愿者(男/女=6/10)随机接受BBD(n=8)或DBD(n=8)分级扩张食道球囊。BBD是通过将5厘米长的高度顺应性气球连接到恒压计上进行的,DBD是通过将5厘米长的气球连接到水平容器上来执行的。间歇性相性球囊扩张以6 mm 汞为增量。对感觉阈值和生物力学特性进行评估和比较。第一感觉阈值(平均±标准差:21±6比21.2±5,mm 汞,P=0.9)、不适(38±8比35±9,P=0.5)和疼痛(44±4比45±3,P=0.7)与BBD和DBD技术相似。然而,与BBD(4/8,50%)相比,更多的受试者耐受DBD(7/8,88%)。气囊用力排入胃内(n=4)、拉扯嘴巴(n=4)、胸部不适(n=2)和呕吐(n=2)是BBD不耐受的重叠原因。两种技术的食管壁扩张性相似。这两种技术都提供了生物力学特性方面的可比数据。然而,在评价食道感觉时,DBD比BBD耐受性更好。因此,我们建议使用DBD进行食道球囊扩张试验。
Esophageal sensation is commonly assessed by barostat-assisted balloon distension (BBD) or dynamic balloon distension (DBD) technique, but their relative merits are unknown. Our aim was to compare the usefulness and tolerability of both techniques. Sixteen healthy volunteers (male/female = 6/10) randomly underwent graded esophageal balloon distensions, using either BBD (n= 8) or DBD (n= 8). BBD was performed by placing a 5-cm long highly compliant balloon attached to a barostat, and DBD by placing a 5-cm long balloon attached to a leveling container. Intermittent phasic balloon distensions were performed in increments of 6 mm Hg. Sensory thresholds and biomechanical properties were assessed and compared. Sensory thresholds for first perception (mean ± standard deviation; 21 ± 6 vs. 21.2 ± 5, mm Hg,P= 0.9), discomfort (38 ± 8 vs. 35 ± 9,P= 0.5), and pain (44 ± 4 vs. 45 ± 3,P= 0.7) were similar with BBD and DBD techniques. However, more subjects tolerated DBD (7/8, 88%) when compared with BBD (4/8, 50%). Forceful expulsion of balloon into stomach (n= 4), pulling around the mouth (n= 4), chest discomfort (n= 2) and retching (n= 2) were overlapping reasons for intolerance with BBD. Esophageal wall distensibility was similar with both techniques. Both techniques provided comparable data on biomechanical properties. However, DBD was better tolerated than BBD for evaluation of esophageal sensation. Hence, we recommend DBD for performing esophageal balloon distension test.