Salvia divinorum: Effects and use among YouTube users

Salvia divinorum: Effects and use among YouTube users
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DOI:
10.1016/j.drugalcdep.2009.11.010
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发表时间:
2010-04-01
影响因子:
4.2
通讯作者:
Clapp, John D.
Clapp, John D.
中科院分区:
医学2区
文献类型:
--
作者:
Lange, James E.;Daniel, Jason;Clapp, John D.

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丹参是一种强烈的、短效的致幻植物,在美国青少年中越来越受欢迎。关于鼠尾草的作用,科学文献很少。广受欢迎的视频分享网站YouTube收到了数千条使用鼠尾草的视频帖子。这项研究的目的是通过对YouTube视频的系统观察来评估使用丹参的效果。用搜索词“salvia”获取鼠尾草视频样本。这些视频被进一步筛选,在这里描述的分析(n=34)中只包括捕捉整个药物“旅行”而没有视频编辑的视频。三名训练有素的研究助理独立观看了视频,并在30-S的间隔内对他们观察到的42种效果进行了评级。症状起病迅速(S通常不到30岁),并在8分钟内消失。此外,丹参剂量与作用时间之间存在关系。由于丹参对人类的影响在很大程度上没有文献记载,这项研究提供了在非实验室环境中(例如,自我录制的视频)中表现出与这种强大的迷幻剂一致的损伤和行为的使用者的观察。此外,这项研究还论证了使用YouTube视频评估新兴药物和药物效果的可行性和缺点。(C)2009爱思唯尔爱尔兰有限公司。保留所有权利。
Salvia divinorum (salvia) is an intense, short-acting hallucinogenic plant gaining popularity among adolescents in the United States. There has been little scientific documentation of salvia's effects. The popular video-sharing website YouTube has received literally thousands of video-posts of people using salvia. The objective of this study was to assess the effects of salvia use through systematic observations of YouTube videos. A sample of salvia videos was obtained using the search term "salvia." The videos were further screened and only videos that captured the entire drug "trip" without video edits were included in the analyses described here (n = 34). Three trained research assistants independently watched the videos and rated their observations on 42 effects in 30-s intervals. Onset of symptoms was quick (often less than 30 s) and tended to dissipate within 8 min. Further, there was a relationship between salvia dose and effect duration. Since salvia's effects on humans are largely undocumented, this study provides the look at users in a non-laboratory environment (e.g. self-taped videos) exhibiting impairments and behaviors consistent with this powerful hallucinogen. Also, this study demonstrates the feasibility and shortcomings of using YouTube videos to assess emerging drugs and drug effects. (C) 2009 Elsevier Ireland Ltd. All rights reserved.