Locomotor dysfunction and risk of cardiovascular disease, quality of life, and medical costs: design of the Locomotive Syndrome and Health Outcome in Aizu Cohort Study (LOHAS) and baseline characteristics of the study population
Locomotor dysfunction and risk of cardiovascular disease, quality of life, and medical costs: design of the Locomotive Syndrome and Health Outcome in Aizu Cohort Study (LOHAS) and baseline characteristics of the study population
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DOI：
10.1007/s00776-012-0200-5
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发表时间：
2012-05-01
影响因子：
1.7
通讯作者：
Konno, Shin-ichi
中科院分区：
文献类型：
--
作者：
Otani, Koji;Takegami, Misa;Konno, Shin-ichi
几乎没有证据表明运动功能障碍的长期结果，例如心血管事件、生活质量和死亡。我们正在进行一项前瞻性队列研究，以评估心血管疾病的风险、生活质量、医疗费用和运动功能障碍导致的死亡率。本研究确定了会津队列研究（LOHAS）的运动综合症和健康结果参与者的基线特征。队列参与者是从日本福岛县南会津镇和只见镇每年在 2008 年至 2010 年间接受当地政府定期健康检查的 40 至 80 岁居民中招募的。肌肉骨骼检查包括颈椎、腰椎、上下肢的体格检查以及身体功能的评估，例如抓握力、单腿站立时间、3米定时起立测试时间。在每年的健康检查中测量心血管危险因素，包括血压和生物参数。我们还进行了一项自填式问卷调查。乐活第一年的参与者包括 1,289 名男性（平均年龄 65.7 岁）和 1,954 名女性（平均年龄 66.2 岁）。肥胖者（体重指数25.0 kg/m(2)）的比例男性为31.9%，女性为34.3%，41.0%的参与者报告患有高血压，7.0%患有糖尿病，43.6%患有高胆固醇血症。男性腰椎管狭窄症的患病率为 10.7%，女性为 12.9%，而男性腰痛的患病率为 15.8%，女性为 17.6%。LOHAS 是一项新型的基于人群的前瞻性队列研究，它将提供一个机会来估计心血管疾病的风险、生活质量、医疗费用和由运动功能障碍引起的死亡率，并提供制定腰痛检测政策所需的流行病学信息。运动功能障碍。
There is little evidence regarding long-term outcomes of locomotor dysfunction such as cardiovascular events, quality of life, and death. We are conducting a prospective cohort study to evaluate risk of cardiovascular disease, quality of life, medical costs, and mortality attributable to locomotor dysfunction. The present study determined baseline characteristics of participants in the Locomotive Syndrome and Health Outcome in Aizu Cohort Study (LOHAS).Cohort participants were recruited from residents between 40 and 80 years old who received regular health check-ups conducted by local government each year between 2008 and 2010 in Minami-Aizu Town and Tadami Town in Fukushima Prefecture, Japan. Musculoskeletal examination included assessment of physical examination of the cervical and lumbar spine, and upper and lower extremities and of physical function, such as grasping power, one-leg standing time, and time for the 3-m timed up-and-go test. Cardiovascular risk factors, including blood pressure and biological parameters, were measured at annual health check-ups. We also conducted a self-administered questionnaire survey.LOHAS participants comprised 1,289 men (mean age 65.7 years) and 1,954 women (mean age 66.2 years) at the first year. The proportion of obese individuals (body mass index 25.0 kg/m(2)) was 31.9% in men and 34.3% in women, and 41.0% of participants reported being followed up for hypertension, 7.0% for diabetes, and 43.6% for hypercholesterolemia. Prevalence of lumbar spinal stenosis was 10.7% in men and 12.9% in women, while prevalence of low back pain was 15.8% in men and 17.6% in women.The LOHAS is a novel population-based prospective cohort study that will provide an opportunity to estimate the risk of cardiovascular disease, quality of life, medical costs, and mortality attributable to locomotor dysfunction, and to provide the epidemiological information required to develop policies for detection of locomotor dysfunction.