Blood pressure levels in the 41 populations of the WHO MONICA Project
Blood pressure levels in the 41 populations of the WHO MONICA Project
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WHO MONICA 项目 41 名人群的血压水平
DOI：
10.1038/sj.jhh.1000531
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发表时间：
1997
影响因子：
2.7
通讯作者：
S. Rywik
中科院分区：
文献类型：
--
作者：
H. K. Wolf;J. Tuomilehto;K. Kuulasmaa;S. Domarkienė;Z. Cepaitis;A. Molarius;S. Sans;A. Dobson;U. Keil;S. Rywik
20世纪80年代初至中期，世卫组织MONICA项目在22个国家的41个研究人群中进行了心血管风险因素调查。年龄在35-64岁的研究人群包括32422名男性和32554名女性。根据标准方案测量血压（BP）和体重指数（BMI）。参与者被问及抗高血压药物。在男性中，人群中收缩压（SBP）的平均年龄标准化血压范围为124至148 mm Hg，舒张压（DBP）为75至93 mm Hg。女性相应的SBP值为118-145 mm Hg，DBP值为74-90 mm Hg。在所有人群中，35-44岁年龄组的女性SBP低于男性。然而，女性的收缩压随着年龄的增长而急剧上升，因此在41个人群中，有34个在55-64岁年龄组中女性的收缩压高于男性。未经治疗的血压严重升高的参与者比例范围为男性4.5%至33.7%，女性1.9%至22.3%。接受抗高血压药物治疗的受试者比例为男性4.3-17.7%，女性6.0-22.0%。这些比例与未经治疗的高血压患者的患病率无关。BMI与SBP相关，男性和女性分别占SBP变异的14%和32%。我们发现在MONICA研究人群中SBP有很大的差异，并得出结论，该结果代表了对血压升高引起的公共卫生问题的有效估计。我们还表明，几乎普遍的问题，血压升高是更普遍的女性比男性，特别是在老年组。
In the early to mid 1980s, the WHO MONICA Project conducted cardiovascular risk factor surveys in 41 study populations in 22 countries. Study populations aged 35–64 years comprised 32 422 men and 32 554 women. Blood pressures (BP) and body mass index (BMI) were measured according to a standard protocol. Participants were asked about antihypertensive medication. In men, the average age-standardized BPs ranged among the populations from 124 to 148 mm Hg for systolic (SBP) and from 75 to 93 mm Hg for diastolic (DBP). The corresponding values in women were 118–145 mm Hg for SBP and 74–90 mm Hg for DBP. In all populations, women had lower SBP than men in the age group 35–44. However, SBP in women rose more steeply with age so that in 34 of 41 populations women had higher SBP than men in the age group 55–64. The proportion of participants with untreated major elevation of BP ranged from 4.5% to 33.7% in men and from 1.9% to 22.3% in women. The proportions of participants receiving antihypertensive medication were 4.3–17.7% for men and 6.0–22.0% for women. These proportions were not correlated with the prevalence of untreated hypertensives. Age-adjusted BMI was associated with SBP and accounted for 14% of the SBP variance in men and 32% in women. We found a large difference in SBP among the MONICA study populations and conclude that the results represent a valid estimate of the public health problem posed by elevated BP. We also have shown that almost universally the problem of elevated BP is more prevalent in women than in men, especially in the older age groups.