Use of the BrainLAB exactrac X-ray 6D system in image-guided radiotherapy
Use of the BrainLAB exactrac X-ray 6D system in image-guided radiotherapy
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DOI：
10.1016/j.meddos.2008.02.005
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发表时间：
2008-06-01
影响因子：
1.2
通讯作者：
Solberg, Timothy D.
中科院分区：
文献类型：
--
作者：
Jin, Jian-Yue;Yin, Fang-Fang;Solberg, Timothy D.
将描述ExacTrac X-Ray 6D图像引导放射治疗（IGRT）系统，并对其性能进行评价。该系统主要集成了2个子系统：（1）基于红外（IR）的光学定位系统（ExacTrac）和（2）射线照相kV x射线成像系统（X-Ray 6D）。红外系统由2个红外摄像机和一个红外反射参考星星组成，红外摄像机用于监测放置在患者皮肤上的反射性身体标记，以帮助患者进行初始设置，其连接到治疗床上，可以帮助治疗床移动，空间分辨率优于0.3 mm。射线照相kV设备由2个倾斜的X射线成像器组成，以获得高分辨率，用于患者位置验证和调整的高质量射线照片。通过使用3自由度（31）或6自由度（6D）融合算法将射线照片与模拟CT图像融合来进行位置验证。根据验证结果使用红外系统执行位置调整。融合算法的可靠性将根据体模和患者研究进行描述。结果表明，如果模拟位置和安装位置之间存在旋转偏差，则6D融合方法优于3D方法。最近，该系统已经增强了由于呼吸而运动的目标的图像引导定位和这些目标的门控治疗的能力。红外标记提供用于跟踪和门控治疗射束的呼吸信号，其中X射线系统在门控递送的整个持续时间内提供相对于门控窗口的患者位置的周期性确认。2008年美国医学剂量学家协会。
The ExacTrac X-Ray 6D image-guided radiotherapy (IGRT) system will be described and its performance evaluated. The system is mainly an integration of 2 subsystems: (1) an infrared (IR)-based optical positioning system (ExacTrac) and (2) a radiographic kV x-ray imaging system (X-Ray 6D). The infrared system consists of 2 IR cameras, which are used to monitor reflective body markers placed on the patient's skin to assist in patient initial setup, and an IR reflective reference star, which is attached to the treatment couch and can assist in couch movement with spatial resolution to better than 0.3 mm. The radiographic kV devices consist of 2 oblique x-ray imagers to obtain high-quality radiographs for patient position verification and adjustment. The position verification is made by fusing the radiographs with the simulation CT images using either 3 degree-of-freedom (31)) or 6 degree-of-freedom (6D) fusion algorithms. The position adjustment is performed using the infrared system according to the verification results. The reliability of the fusion algorithm will be described based on phantom and patient studies. The results indicated that the 6D fusion method is better compared to the 3D method if there are rotational deviations between the simulation and setup positions. Recently, the system has been augmented with the capabilities for image-guided positioning of targets in motion due to respiration and for gated treatment of those targets. The infrared markers provide a respiratory signal for tracking and gating of the treatment beam, with the x-ray system providing periodic confirmation of patient position relative to the gating window throughout the duration of the gated delivery. 0 2008 American Association of Medical Dosimetrists.