Mixed infections with Opisthorchis viverrini and intestinal flukes in residents of Vientiane Municipality and Saravane Province in Laos
Mixed infections with Opisthorchis viverrini and intestinal flukes in residents of Vientiane Municipality and Saravane Province in Laos
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DOI：
10.1079/joh2005302
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发表时间：
2005-09-01
影响因子：
1.6
通讯作者：
Rim, HJ
中科院分区：
文献类型：
--
作者：
Chai, JY;Park, JH;Rim, HJ
对老挝沿着湄公河的万象市和沙拉湾省两个滨江地区的1869人进行了粪便蠕虫卵检查。为了获得成虫吸虫，对42名小吸虫卵（猫尾丝虫卵、异形虫卵或卵枝虫卵）呈阳性的人使用20-30 mg/kg（-1）单剂量的吡喹酮进行治疗并清除。然后从36人（每个地区18人）收集腹泻粪便，并使用立体显微镜搜索蠕虫寄生虫。粪便检查显示，万象省和沙捞越省的小吸虫卵阳性率分别为53.3%和70.8%（平均65.2%）。感染O.结果表明，该地区共发现6种肠吸虫，分别为太湖单棘吸虫（Hapleliis taichui）、太湖单棘吸虫（H. pumilio，H. yokogawai、犬棘鲷、Prosthodendrium molenkampi和Bonnei棘鲷。两个地点的吸虫总数和种类比例有显著差异，万象为1041 O. viverrini（57.8只/人）和其他615只（34.2只/人）; viverrini（21.9/人）和其他155207人（8622.6/人）。五个来自Saravane的人没有O。灵猫属，但有许多异形和/或lecithodendriid吸虫。结果表明，O.灵猫和几种异型和lecithodendriid吸虫在这两个滨江地区是地方性的，并建议感染的强度和吸虫物种的相对比例沿着湄公河流域的地方不同。
Faecal examinations for helminth eggs were performed on 1869 people from two riverside localities, Vientiane Municipality and Saravane Province, along the Mekong River, Laos. To obtain adult flukes, 42 people positive for small trematode eggs (Opisthorchis viverrini, heterophyid, or lecithodendriid eggs) were treated with a 20-30 mg kg(-1) single dose of praziquantel and purged. Diarrhoeic stools were then collected from 36 people (18 in each area) and searched for helminth parasites using stereomicroscopes. Faecal examinations revealed positive rates for small trematode eggs of 53.3% and 70.8% (average 65.2%) in Vientiane and Saravane Province, respectively. Infections with O. viverrini and six species of intestinal flukes were found, namely, Haplorchis taichui, H. pumilio, H. yokogawai, Centrocestus caninus, Prosthodendrium molenkampi, and Phaneropsolus bonnei. The total number of flukes collected and the proportion of fluke species recovered were markedly different in the two localities; in Vientiane, 1041 O. viverrini (57.8 per person) and 615 others (34.2 per person), whereas in Saravane, 395 O. viverrini (21.9 per person) and 155207 others (8622.6 per person). Five people from Saravane harboured no O. viverrini but numerous heterophyid and/or lecithodendriid flukes. The results indicate that O. viverrini and several species of heterophyid and lecithodendriid flukes are endemic in these two riverside localities, and suggest that the intensity of infection and the relative proportion of fluke species vary by locality along the Mekong River basin.