Acrylonitrile induces autolysis Bacillus subtilis.
Acrylonitrile induces autolysis Bacillus subtilis.
复制标题
丙烯腈诱导枯草芽孢杆菌自溶。
DOI：
10.1111/j.1574-6968.2000.tb08904.x
复制
发表时间：
2000
影响因子：
2.1
通讯作者：
Doyle,RJ
中科院分区：
文献类型：
--
作者：
Reyes,GF;Corbett,D;Benz,FW;Doyle,RJ
丙烯腈（AN）是一种工业化学品，用于制造塑料和其他聚合物。据报道，AN是一种急性毒素，是啮齿动物的已知致癌物质。当AN与枯草芽孢杆菌的悬浮液混合时，细菌开始自溶。它被确定为AN部分转化为氰化物，一个强的质子载体在B。枯草杆菌。B.当质子动力消失时，subtilisbecomes活跃。然而，AN产生的氰化物的量不足以促进指数B中的自溶。枯草芽孢杆菌这是首次报道AN可诱导细菌自溶反应。推测B.枯草杆菌可能在AN的环境监测中是有用的。此外，细菌对AN的代谢可能有助于生物修复。
Acrylonitrile (AN) is an industrial chemical used in the manufacture of plastics and other polymers. AN has been reported to be an acute toxin and is a known carcinogen in rodents. When AN was mixed with suspensions ofBacillus subtilis, the bacteria began autolysis. It was determined that AN is partially converted to cyanide, a strong protonophore inB. subtilis. Autolytic enzymes inB. subtilisbecome active when the protonmotive force is dissipated. The amount of cyanide produced from AN, however, was not enough to promote autolysis in exponentialB. subtilis. This is the first report showing that AN may induce autolytic reactions in bacteria. It is suggested the autolysis ofB. subtilismay be useful in the environmental monitoring of AN. In addition, the metabolism of AN by bacilli may be useful in bioremediation.