2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training
2-D DIGE analysis of the mitochondrial proteome from human skeletal muscle reveals time course-dependent remodelling in response to 14 consecutive days of endurance exercise training
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DOI：
10.1002/pmic.201000597
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发表时间：
2011-04-01
期刊：
影响因子：
3.4
通讯作者：
O'Gorman, Donal J.
中科院分区：
文献类型：
--
作者：
Egan, Brendan;Dowling, Paul;O'Gorman, Donal J.
骨骼肌对反复的耐力运动的适应增加了有氧能力，改善了线粒体功能。然而，人骨骼肌线粒体蛋白质组对短期耐力运动训练的适应性尚未见报道。8名男性久坐者连续14天每天以80%的最大耗氧量（VO2peak）骑自行车60 min，导致VO2peak增加17.5 ± 3.8%（p
Adaptation of skeletal muscle to repeated bouts of endurance exercise increases aerobic capacity and improves mitochondrial function. However, the adaptation of human skeletal muscle mitochondrial proteome to short-term endurance exercise training has not been investigated. Eight sedentary males cycled for 60 min at 80% of peak oxygen consumption (VO2peak) each day for 14 consecutive days, resulting in an increase in VO2peak of 17.5 +/- 3.8% (p