Excessive daytime sleepiness in cervical dystonia.
Excessive daytime sleepiness in cervical dystonia.
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颈部肌张力障碍导致白天过度嗜睡。
DOI：
10.1016/j.parkreldis.2009.04.007
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发表时间：
2009
影响因子：
4.1
通讯作者：
S. Factor
中科院分区：
文献类型：
--
作者：
L. Trotti;Christine D. Esper;P. Feustel;D. Bliwise;S. Factor
很少有研究检查颈部肌张力障碍（CD）患者的睡眠。我们评估了43例连续CD患者、19例其他局灶性运动障碍患者和49例年龄和性别匹配的健康对照者是否存在过度日间嗜睡（通过埃普沃思嗜睡量表（ESS）测量）。所有患者均接受肉毒杆菌毒素治疗。我们发现，CD患者ESS评分>11的异常百分比高于两个对照组中的任何一个（21% vs. 0% vs. 4%，与CD组的每对比较p < 0.05）。使用抗胆碱能药物是CD组嗜睡增加的部分原因，但不是全部原因。年龄、性别、种族、多伦多西部痉挛性斜颈评定量表（TWSTRS）评分或其分项评分（严重程度、残疾和疼痛）以及其他常用药物（苯二氮卓类药物、抗抑郁药）与ESS评分增加无关。在相当一部分CD患者中，白天过度嗜睡的初步发现表明，对CD患者睡眠障碍的进一步调查是必要的。
Few investigations have examined sleep in cervical dystonia (CD) patients. We assessed 43 consecutive CD patients, 19 patients with other focal movement disorders, and 49 healthy, age- and gender-matched controls for the presence of excessive daytime sleepiness (as measured by the Epworth Sleepiness Scale, ESS). All patients were receiving botulinum toxin. We found that a higher percentage of CD patients had abnormal ESS scores of >11 than did either of the two control groups (21% vs. 0% vs. 4%, p < 0.05 for each pairwise comparison with the CD group). Use of anticholinergic medications accounted for some but not all of this increase in sleepiness in the CD group. Age, gender, race, scores on the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) or its subscores (severity, disability, and pain), and other common medication use (benzodiazepines, antidepressants) were not associated with increased ESS scores. This preliminary finding of excessive daytime sleepiness in a substantial portion of CD patients suggests that further investigation into disordered sleep in CD is warranted.
扭转肌张力障碍的多导睡眠图。
影响因子：
--
作者：
Jankel,WR;Niedermeyer,E;Graf,M;Kalsher,M
通讯作者：
Kalsher,M