EEG correlates of spatial orientation in the human retrosplenial complex
EEG correlates of spatial orientation in the human retrosplenial complex
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DOI：
10.1016/j.neuroimage.2015.07.009
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发表时间：
2015-10-15
期刊：
影响因子：
5.7
通讯作者：
Gramann, K.
中科院分区：
文献类型：
--
作者：
Lin, C-T.;Chiu, T-C.;Gramann, K.
空间导航的研究可靠地表明，压后复合体（RSC）通过将自我中心和非自我中心的空间信息转换到各自的其他空间参考框架（SRF）中，在非自我中心的空间信息处理中起着关键作用。虽然越来越多的成像研究调查的RSC在空间任务中的作用，高时间分辨率的措施，如脑电图（EEG）是缺失的。为了研究RSC在高时间分辨率空间导航中的作用，我们利用EEG分析了基于非自我中心和自我中心SRF的导航过程中的频谱扰动。参与者在一个结构清晰的虚拟环境中进行路径整合任务，提供异感信息。连续脑电记录进行分解的独立分量分析（伊卡）与独立的时间源序列，使用等效偶极子模型的后续源重建。时间-频率变换被用来调查参考框架特定的方向过程中导航相比，控制条件相同的视觉输入，但没有方向任务。我们的研究结果表明，导航基于自我中心的参考框架招募了一个网络，包括顶叶，运动，枕叶皮层与主导扰动的α波段和θ调制额叶皮层。在RSC中，Allocentric导航伴随着8-13 Hz频带的性能相关去极化和12-14 Hz频带的同步。这些结果支持了这样的说法，即压后复合体是将以自我为中心的空间信息转化为以他人为中心的参考框架的核心。在RSC中具有不同时间过程的不同频率的调制进一步提供了两个不同神经过程的第一证据，这两个不同的神经过程反映了基于不同参考系的空间信息的翻译和航向变化的计算。(C)2015 Elsevier Inc. All rights reserved.
Studies on spatial navigation reliably demonstrate that the retrosplenial complex (RSC) plays a pivotal role for allocentric spatial information processing by transforming egocentric and allocentric spatial information into the respective other spatial reference frame (SRF). While more and more imaging studies investigate the role of the RSC in spatial tasks, high temporal resolution measures such as electroencephalography (EEG) are missing. To investigate the function of the RSC in spatial navigation with high temporal resolution we used EEG to analyze spectral perturbations during navigation based on allocentric and egocentric SRF. Participants performed a path integration task in a clearly structured virtual environment providing allothetic information. Continuous EEG recordings were decomposed by independent component analysis (ICA) with subsequent source reconstruction of independent time source series using equivalent dipole modeling. Time-frequency transformation was used to investigate reference frame-specific orientation processes during navigation as compared to a control condition with identical visual input but no orientation task. Our results demonstrate that navigation based on an egocentric reference frame recruited a network including the parietal, motor, and occipital cortices with dominant perturbations in the alpha band and theta modulation in frontal cortex. Allocentric navigation was accompanied by performance-related desynchronization of the 8-13 Hz frequency band and synchronization in the 12-14 Hz band in the RSC. The results support the claim that the retrosplenial complex is central to translating egocentric spatial information into allocentric reference frames. Modulations in different frequencies with different time courses in the RSC further provide first evidence of two distinct neural processes reflecting translation of spatial information based on distinct reference frames and the computation of heading changes. (C) 2015 Elsevier Inc. All rights reserved.