Reemergence of the HIV Epidemic Among Men Who Have Sex With Men in North America, Western Europe, and Australia, 1996-2005
Reemergence of the HIV Epidemic Among Men Who Have Sex With Men in North America, Western Europe, and Australia, 1996-2005
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DOI：
10.1016/j.annepidem.2009.03.004
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发表时间：
2009-06-01
影响因子：
5.6
通讯作者：
Fenton, Kevin A.
中科院分区：
文献类型：
--
作者：
Sullivan, Patrick S.;Hamouda, Osamah;Fenton, Kevin A.
目得：描述8个国家男男性行为者（MSM）中人类免疫缺陷病毒（HIV）报告率的变化并说明其背景（澳大利亚、加拿大、法国、德国、荷兰、西班牙、英国和美国）。我们通过广义线性回归分析了1996-2000年和2000-2005年艾滋病毒报告率的趋势，并估计了艾滋病毒报告率的年度百分比变化（EAPC）。为了解释趋势，我们直观地检查了MSM中一期和二期梅毒报告的图表以及最近HIV检测的流行率。（95%置信区间[CI]：-5.8%，-4.7%），从1996-2000年，每年增加3.3%（95% CI：+2.9%，3.7%），从2000-2005年。在增加艾滋病毒诊断期间，发生在男男性行为者之间的初级和二级梅毒诊断增加，但最近的艾滋病毒检测男男性行为者之间似乎并没有增加。结论：在20世纪90年代后半期下降后，男男性行为者的艾滋病毒通知率增加，从2000年开始。MSM中艾滋病毒通知的增加并不能完全由艾滋病毒检测的变化来解释。迫切需要作出努力，为男男性行为者制定有效的艾滋病毒预防干预措施，并在这些国家广泛实施。Ann Epidemiol 2009;19：423-431. (c)2009 Elsevier Inc. All rights reserved.
PURPOSE: To describe and contextualize changes in rates of human immunodeficiency virus (HIV) notifications in men who have sex with men (MSM) in eight countries (Australia, Canada, France, Germany, Netherlands, Spain, United Kingdom, and United States) from 1996-2005.METHODS: We analyzed trends in HIV notification rates from 1996-2000 and 2000-2005 by generalized linear regression and estimated annual percentage change (EAPC) in rates of HIV notifications. To interpret trends, we visually examined graphs of primary and secondary syphilis reports among MSM and the prevalence of recent HIV testing.RESULTS: The rate of HIV notifications among MSM declined 5.2% per year (95% confidence interval [CI]: -5.8%, -4.7%) from 1996-2000, and increased 3.3% per year (95% Cl: +2.9%,+3.7%) from 2000-2005. During the period of increasing HIV diagnoses, increases in primary and secondary syphilis diagnoses occurred among MSM, but recent HIV testing among MSM did not seem to increase.CONCLUSIONS: After declining in the second half of the 1990s, HIV notification rates for MSM increased beginning in 2000. Increased HIV notifications in MSM are not wholly explained by changes in HIV testing. Urgent efforts are required to develop effective HIV prevention interventions for MSM, and implement them broadly in these Countries. Ann Epidemiol 2009;19:423-431. (c) 2009 Elsevier Inc. All rights reserved.