Somatosensory processing in neurodevelopmental disorders
Somatosensory processing in neurodevelopmental disorders
复制标题
DOI：
10.1007/s11689-010-9046-3
复制
发表时间：
2010-06-01
影响因子：
4.9
通讯作者：
Cascio, Carissa J.
中科院分区：
文献类型：
--
作者：
Cascio, Carissa J.
本文的目的是审查的作用，躯体感觉知觉在典型的发展，其畸变在一系列的神经发育障碍，触觉处理异常和中央功能的每一个障碍，如运动，通信和社会发展之间的潜在关系。选择代表一系列症状和病因的神经发育障碍，并且已经发表了多篇关于体感差异的同行评议文章，以纳入综述。在动物模型中的相关研究，以及早期感觉剥夺的条件，也包括在内。躯体感觉加工在典型的发育中起着重要但经常被忽视的作用，并且在各种神经发育障碍中是异常的。这在对脆性X综合征、自闭症谱系障碍（ASD）、注意缺陷多动障碍（ADHD）和脑瘫（CP）儿童样本的行为、感觉阈值、神经解剖学和神经生理学研究中得到了证实。躯体感觉处理受损见于一系列神经发育障碍，并与这些障碍中的沟通、运动能力和社交技能缺陷相关。鉴于触觉在早期发育中的核心作用，实验和临床方法都应考虑体感处理在神经发育障碍的病因学和治疗中的作用。
The purpose of this article is to review the role of somatosensory perception in typical development, its aberration in a range of neurodevelopmental disorders, and the potential relations between tactile processing abnormalities and central features of each disorder such as motor, communication, and social development. Neurodevelopmental disorders that represent a range of symptoms and etiologies, and for which multiple peer-reviewed articles on somatosensory differences have been published, were chosen to include in the review. Relevant studies in animal models, as well as conditions of early sensory deprivation, are also included. Somatosensory processing plays an important, yet often overlooked, role in typical development and is aberrant in various neurodevelopmental disorders. This is demonstrated in studies of behavior, sensory thresholds, neuroanatomy, and neurophysiology in samples of children with Fragile X syndrome, autism spectrum disorders (ASD), attention deficit hyperactivity disorder (ADHD), and cerebral palsy (CP). Impaired somatosensory processing is found in a range of neurodevelopmental disorders and is associated with deficits in communication, motor ability, and social skills in these disorders. Given the central role of touch in early development, both experimental and clinical approaches should take into consideration the role of somatosensory processing in the etiology and treatment of neurodevelopmental disorders.