A facile fluorescent "turn-off' method for sensing paraquat based on pyranine-paraquat interaction
A facile fluorescent "turn-off' method for sensing paraquat based on pyranine-paraquat interaction
复制标题
基于吡喃-百草枯相互作用的一种简便的荧光“关闭”方法，用于检测百草枯
DOI：
10.1016/jsaa.2018.03.042
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Zhang Zipin
中科院分区：
文献类型：
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作者：
Zhao Zuzhi;Zhang Fengwei;Zhang Zipin
由于其高度的临床和环境相关性，开发一种技术简单但有效的百草枯 (PQ) 检测方法具有重要意义。在这项研究中，我们开发了一种基于吡喃-PQ相互作用的基于吡喃的荧光“关闭”方法，用于PQ传感。我们研究了该方法的分析性能对实验条件（如离子强度、介质 pH 值等）的依赖性。在优化的条件下，该方法具有灵敏性和选择性，可用于实际样品中的PQ检测。这项研究本质上为 PQ 传感提供了一种易于使用的荧光系统，该系统便宜、稳定且技术简单，并且有望找到更有趣的临床和环境应用。
Development of a technically simple yet effective method for paraquat (PQ) detection is of great importance due to its high clinical and environmental relevance. In this study, we developed a pyranine-based fluorescent “turn-off” method for PQ sensing based on pyranine-PQ interaction. We investigated the dependence of analytical performance of this method on the experimental conditions, such as the ion strength, medium pH, and so on. Under the optimized conditions, the method is sensitive and selective, and could be used for PQ detection in real-world sample. This study essentially provides a readily accessible fluorescent system for PQ sensing which is cheap, robust, and technically simple, and it is envisaged to find more interesting clinical and environmental applications..