Effects of ascorbate on insoluble elastin accumulation and cross-link formation in rabbit pulmonary artery smooth muscle cultures.
Effects of ascorbate on insoluble elastin accumulation and cross-link formation in rabbit pulmonary artery smooth muscle cultures.
复制标题
抗坏血酸对兔肺动脉平滑肌培养物中不溶性弹性蛋白积累和交联形成的影响。
DOI：
10.1021/bi00261a001
复制
发表时间：
1982
期刊：
影响因子：
2.9
通讯作者：
Franzblau,C
中科院分区：
文献类型：
--
作者：
Dunn,DM;Franzblau,C
Diane M.Dunn*和Carl Franzblau摘要：体外培养的断奶兔肺内膜血管平滑肌细胞在有或无抗坏血酸钠的条件下培养。对结缔组织成分、不溶性弹性蛋白和胶原蛋白进行鉴定和定量。-氨基己二酸-半醛(大蒜素)和分子间交联物桥连素(DES)、异桥连素(IDES)和羟醛缩合产物(Aldol)的形成和积累从
Diane M. Dunn* and Carl Franzblau abstract: Cultured pulmonary artery smooth muscle cells derived from the medial vessel layer of weanling rabbits were grown in thepresence or absence of sodium ascorbate. The connective tissue elements insoluble elastin and collagen were identified and quantified. Formation and accumulátion of-aminoadipic acid-semialdehyde (allysine) and the intermolecular cross-links desmosine (Des), isodesmosine (Ides), and aldol condensation product (Aldol) were evaluated from