HIV and Aging in Mainland China: Implications for Control and Prevention Research
HIV and Aging in Mainland China: Implications for Control and Prevention Research
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中国大陆的艾滋病毒与老龄化：对控制和预防研究的影响
DOI：
10.1007/s11904-019-00473-2
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发表时间：
2019-12-01
影响因子：
4.6
通讯作者：
Wong, Frank Y.
中科院分区：
文献类型：
--
作者：
He, Na;Ding, Yingying;Wong, Frank Y.
回顾的目的在过去的15年里，随着治疗和护理的改善，中国的艾滋病相关流行病学发生了巨大的变化。通过适当的治疗，艾滋病毒现在被认为是一种慢性疾病。因此，许多艾滋病毒感染者（PLWH）现在出现与年龄相关的合并症。我们回顾了13个热点问题的流行病学与艾滋病病毒在中国大陆。ResultsMany的老龄化相关的问题与艾滋病病毒感染的生物和物理方面在中国大陆解决的全球文献是一致的。在PLWH中观察到年龄相关合并症的患病率更高。除了与艾滋病毒感染和传统的危险因素相关的生物机制，其他因素发挥了重要作用，在老化过程中PLWH.SummaryA更强的重点筛查，预防和管理非艾滋病毒共病之间PLWH现在是必要的。宏观社会因素需要纳入下一代临床和/或行为艾滋病毒研究，以告知疾病进展和管理以及预防。
Purpose of ReviewThe last 15 years have witnessed a dramatic change in HIV-related epidemiology amidst improvements in treatment and care in China. With proper treatment, HIV is now considered a chronic disease. As a consequence, many people living with HIV (PLWH) now present age-related comorbidities. We reviewed 13 topical issues concerning the epidemiology of aging with HIV in mainland China.ResultsMany of aging-related issues associated with the biological and physical aspects of living with HIV addressed in mainland China are consistent with the global literature. Greater prevalence of age-related comorbidities among PLWH was observed. Beyond biological mechanisms associated with HIV infection and traditional risk factors, other factors play a vital role in the aging process among PLWH.SummaryA stronger focus on screening, prevention, and management of non-HIV co-morbidities among PLWH is now warranted. Macro-social factors need to be integrated into next generation of clinical and/or behavioral HIV research to inform disease progression and management as well as prevention.