Nanoformulation of natural products for prevention and therapy of prostate cancer.
Nanoformulation of natural products for prevention and therapy of prostate cancer.
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DOI：
10.1016/j.canlet.2012.11.037
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发表时间：
2013-06-28
期刊：
影响因子：
9.7
通讯作者：
Mukhtar, Hasan
中科院分区：
文献类型：
--
作者：
Sanna, Vanna;Siddiqui, Imtiaz A.;Sechi, Mario;Mukhtar, Hasan
需要开发用于治疗前列腺癌的改进的治疗选择，其能够抑制癌前病变和恶性病变的增殖和/或提高常规化学预防剂和化疗剂的有效性。从这个角度来看，正在积极研究应用基于纳米技术的策略来递送天然化合物以有效控制疾病。在这里，在强调用于前列腺癌化学预防和化疗的最有前途的天然化合物之后，讨论了最先进的纳米治疗方法和最近的“纳米化学预防”概念验证，以及用于前列腺癌治疗的有希望的靶向纳米原型的临床开发。
There is a need for developing improved therapeutic options for the management of prostate cancer, able to inhibit proliferation of precancerous and malignant lesions and/or to improve the effectiveness of conventional chemopreventive and chemotherapeutic agents. In this perspective, application of nanotechnology based strategies for the delivery of natural compounds for effective management of the disease is being actively researched. Here, after highlighting the most promising natural compounds for chemoprevention and chemotherapy of prostate cancer, the state of the art nanotherapeutics and the recent proof-of-concept of “nanochemoprevention”, as well as the clinical development of promising targeted nanoprototypes for use in the prostate cancer treatment are being discussed.
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影响因子：
4.9
作者：
Alexis F;Pridgen E;Molnar LK;Farokhzad OC
通讯作者：
Farokhzad OC
影响因子：
11.5
作者：
Adhami, Vaqar Mustafa;Malik, Arshi;Mukhtar, Hasan
通讯作者：
Mukhtar, Hasan
影响因子：
4.2
作者：
Adhami, VM;Ahmad, N;Mukhtar, H
通讯作者：
Mukhtar, H
影响因子：
14
作者：
Cheng, Jianjun;Teply, Benjamin A.;Farokhzad, Omid C.
通讯作者：
Farokhzad, Omid C.
DOI：
10.1158/1078-0432.ccr-08-2332
发表时间：
2009-03-15
期刊：
Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子：
--
作者：
Adhami VM;Siddiqui IA;Sarfaraz S;Khwaja SI;Hafeez BB;Ahmad N;Mukhtar H
通讯作者：
Mukhtar H