An examination of neuroticism as a moderating factor in the association of positive and negative schizotypy with psychopathology in a nonclinical sample
An examination of neuroticism as a moderating factor in the association of positive and negative schizotypy with psychopathology in a nonclinical sample
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DOI：
10.1016/j.schres.2009.09.021
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发表时间：
2009-12-01
影响因子：
4.5
通讯作者：
Kwapil, Thomas R.
中科院分区：
文献类型：
--
作者：
Barrantes-Vidal, Neus;Ros-Morente, Agnes;Kwapil, Thomas R.
神经质等人格特征与精神分裂症和精神分裂症有关。然而，迄今为止的研究尚未阐明神经质与个体精神分裂维度的差异关联及其在精神分裂症谱系精神病理学表达中所起的作用。 204 名非临床确定的参与者完成了评估神经质以及正向和负向精神分裂维度的自我报告问卷，并接受了结构化访谈，评估精神分裂症谱系精神病理学（类似精神病的经历、阴性症状、A 类人格障碍和特征）、情绪发作、药物滥用和整体功能。结果表明，神经质可以预测精神分裂症和抑郁症的阳性症状，超出了这两种精神分裂症维度的影响。此外，神经质调节了阳性精神分裂症与精神病理学和功能的访谈测量的关联。这项研究的结果与其他研究一致，表明神经质在病因学上与精神分裂症谱系精神病理学相关，并且不能仅将其视为谱系障碍的“继发效应”。当前的精神病心理学模型可以适应神经质作为情感障碍和精神障碍的共同脆弱因素的发现。 (C) 2009 Elsevier B.V. 保留所有权利。
Personality traits such as neuroticism are associated with schizophrenia and schizotypy. However, studies thus far have not clarified the differential association of neuroticism with individual schizotypy dimensions and the role it plays in the expression of schizophrenia-spectrum psychopathology. 204 nonclinically ascertained participants completed self-report questionnaires assessing neuroticism and the positive and negative schizotypy dimensions, and underwent structured interviews assessing schizophrenia-spectrum psychopathology (psychotic-like experiences, negative symptoms, cluster A personality disorders and traits), mood episodes, substance abuse, and global functioning. Results indicated that neuroticism predicted positive symptoms of schizophrenia and depression, over-and-above the effects of both schizotypy dimensions. Also, neuroticism moderated the association of positive schizotypy with interview measures of psychopathology and functioning. The results of this study are consistent with other research indicating that neuroticism is etiologically relevant for schizophrenia-spectrum psychopathology and that it cannot be considered solely a 'secondary effect' of spectrum disorders. Current psychological models of psychosis can accomodate the finding of neuroticism being a shared vulnerability factor for affective and psychotic disorders. (C) 2009 Elsevier B.V. All rights reserved.