Prevention of vaginal dryness in perimenopausal women. Supplementation with Lady Prelox
Prevention of vaginal dryness in perimenopausal women. Supplementation with Lady Prelox
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DOI：
10.23736/s0026-4784.19.04466-6
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发表时间：
2019-12-01
影响因子：
1
通讯作者：
Ledda, Andrea
中科院分区：
文献类型：
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作者：
Cesarone, Maria R.;Belcaro, Gianni;Ledda, Andrea
背景：这项试点注册研究的目的是使用包含碧萝芷 (R)、L-精氨酸、L-瓜氨酸和玫瑰果提取物的标准化补充剂（Lady Prelox (R)，Horphag Research）来改善下午和绝经后健康女性与阴道干燥相关的体征和症状。一组女性仅使用标准管理 (SM)，第二组添加 Lady Prelox (R)。 方法：本研究包括四组女性。 34 名绝经前妇女和 38 名绝经后妇女服用 Lady Prelox (R)，每天四片，持续 8 周，33 名绝经前妇女和 35 名绝经后妇女作为对照。 结果：该补充剂没有观察到安全问题，耐受性良好。对照组和补充受试者的亚组在绝经前和绝经后组中具有可比性。在绝经前女性中，与对照组相比，服用补充剂后女性性功能指数（FSFI）结果显着改善（P
BACKGROUND: The aim of this pilot registry study was to use a standardized supplement (Lady Prelox (R), Horphag Research) including Pycnogenol (R), l-arginine, L-citrulline and rose hip extract to improve signs and symptoms associated with vaginal dryness in pm and post-menopausal healthy women. A group of women used only a standard management (SM) and a second group added Lady Prelox (R).METHODS: Four groups of women were included in the study. 34 pre-menopausal and 38 post-menopausal women took Lady Prelox (R), four tablets daily for 8 weeks and 33 pre-menopausal women and 35 post-menopausal women served as controls.RESULTS: No safety problems were observed with the supplement that was well tolerated. The subgroups of controls and supplemented subjects were comparable in both the pre- and post-menopausal groups. Among pm-menopausal women, results of the female sexual function index (FSFI) were significantly improved with the supplement in comparison with the control subjects' group (P