POTENTIAL METAL-BINDING DOMAINS IN NUCLEIC-ACID BINDING-PROTEINS
POTENTIAL METAL-BINDING DOMAINS IN NUCLEIC-ACID BINDING-PROTEINS
复制标题
DOI：
10.1126/science.2421409
复制
发表时间：
1986-04-25
期刊：
影响因子：
56.9
通讯作者：
BERG, JM
中科院分区：
文献类型：
--
作者：
BERG, JM
系统的搜索序列，可能会形成金属结合结构域的蛋白质已经进行。五类参与核酸结合或基因调控的蛋白质被发现含有这样的序列。这些观察结果表明，许多实验旨在确定金属结合域是否存在于这些蛋白质中，如果存在，这些结构域在核酸结合和基因调控过程中发挥什么作用。
A systematic search for sequences that potentially could form metal-binding domains in proteins has been performed. Five classes of proteins involved in nucleic acid binding or gene regulation were found to contain such sequences. These observations suggest numerous experiments aimed at determining whether metal-binding domains are present in these proteins and, if present, what roles such domains play in the processes of nucleic acid binding and gene regulation.