Effect of angiotensin-converting enzyme insertion/deletion polymorphism DD genotype on high-frequency heart rate variability in African Americans
Effect of angiotensin-converting enzyme insertion/deletion polymorphism DD genotype on high-frequency heart rate variability in African Americans
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DOI：
10.1016/j.amjcard.2003.08.069
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发表时间：
2003-12-15
影响因子：
2.8
通讯作者：
Abernethy, DR
中科院分区：
文献类型：
--
作者：
Thayer, JF;Merritt, MM;Abernethy, DR
79名非洲裔美国人参与了生命周期多样性社区健康老龄化（HANDLS）试点研究，对血管紧张素转换酶（ACE）插入/缺失（I/D）多态性进行基因分型，并对其高频（HF）心率变异性（HRV）进行频谱功率分析。由快速傅里叶变换确定。11例HF HRV最高，ID居中，DD最低（11 vs DD，p
Seventy-nine African-American participants in the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) pilot study were genotyped for the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and had spectral power of their high-frequency (HF) heart rate variability (HRV). determined by fast-Fourier transformation. HF HRV was highest in 11,- intermediate in ID, and lowest in DD (11 vs DD, p