Population-level HIV declines and behavioral risk avoidance in Uganda
Population-level HIV declines and behavioral risk avoidance in Uganda
复制标题
DOI：
10.1126/science.1093166
复制
发表时间：
2004-04-30
期刊：
影响因子：
56.9
通讯作者：
Low-Beer, D
中科院分区：
文献类型：
--
作者：
Stoneburner, RL;Low-Beer, D
乌干达提供了最明显的例子，表明如果动员民众避免风险，人类免疫缺陷病毒（HIV）是可以预防的。尽管资源有限，但自 20 世纪 90 年代初以来，乌干达的艾滋病毒感染率下降了 70%，这与随意性行为减少了 60% 有关。乌干达的反应似乎与通过社交网络传播获得性免疫缺陷综合症（艾滋病）有关。尽管大量使用安全套并推广生物医学方法，但其他非洲国家既没有表现出类似的行为反应，也没有出现同样规模的艾滋病毒感染率下降。乌干达的成功相当于疫苗的有效性达到80%。其复制将需要改变全球艾滋病毒/艾滋病干预政策及其评估。
Uganda provides the clearest example that human immunodeficiency virus (HIV) is preventable if populations are mobilized to avoid risk. Despite limited resources, Uganda has shown a 70% decline in HIV prevalence since the early 1990s, linked to a 60% reduction in casual sex. The response in Uganda appears to be distinctively associated with communication about acquired immunodeficiency syndrome (AIDS) through social networks. Despite substantial condom use and promotion of biomedical approaches, other African countries have shown neither similar behavioral responses nor HIV prevalence declines of the same scale. The Ugandan success is equivalent to a vaccine of 80% effectiveness. Its replication will require changes in global HIV/AIDS intervention policies and their evaluation.