Impact of COVID-19 Outbreak on Cancer Patient Care and Treatment: Data from an Outpatient Oncology Clinic in Lombardy (Italy).
Impact of COVID-19 Outbreak on Cancer Patient Care and Treatment: Data from an Outpatient Oncology Clinic in Lombardy (Italy).
复制标题
DOI：
10.3390/cancers12102941
复制
发表时间：
2020-10-12
期刊：
影响因子：
5.2
通讯作者：
Sottotetti F
中科院分区：
文献类型：
--
作者：
Quaquarini E;Saltalamacchia G;Presti D;Caldana G;Tibollo V;Malovini A;Palumbo R;Teragni CM;Balletti E;Mollica L;Biscaldi E;Frascaroli M;Bernardo A;Sottotetti F
据报道，在COVID-19大流行期间，癌症是导致不良后果和死亡的主要风险因素。本研究的目的是调查2019冠状病毒病大流行期间癌症患者的管理和肿瘤治疗，并描述ICS Maugeri门诊诊所（意大利帕维亚）实施的遏制措施。与前四年同期进行了比较。在2020年至2019年期间，治疗可及性显著减少，但在2020年至2018年、2017年或2016年期间没有出现这种情况。2020年，“大流行恐惧”是延误治疗的最常见原因。只有少数患者患上了COVID-19。与其他所有年份相比，2020年的放射检查数量显著减少。我们的癌症患者中COVID-19的发病率很低，加上医院控制感染的政策，使大多数患者能够获得安全的癌症治疗和持续的护理。伦巴第是意大利第一个在2020年初爆发冠状病毒病19 （COVID-19）的地区。在这种情况下，据报道，癌症是不良后果和死亡的主要危险因素，因此肿瘤学会迅速发布了大流行期间癌症护理指南。本研究的目的是调查2019冠状病毒病大流行期间癌症患者的管理和肿瘤治疗，并描述我们在帕维亚（伦巴第）门诊诊所采取的遏制措施。并与前4年（2019年、2018年、2017年、2016年）同期进行了比较。利用我们的电子数据库，我们评估了2020年2月24日至2020年4月30日期间到医院输注抗癌药物的患者数量和特征，以及进行放射检查的数量。尽管与2019年相比，获得治疗的人数显著减少（2590人对2974人，获得率比(ARR) = 0.85, p < 0.001），但2020年与2018年、2017年或2016年之间，获得治疗的人数和ARR没有明显差异（2590人对2626人（ARR = 0.07）、2660人（ARR = 0.99）和2694人（ARR = 0.96），分别为p < 0.05）。2020年，63名患者延迟治疗：38%是因为“大流行恐惧”，18%是因为旅行限制，13%是因为隔离，18%是因为COVID-19以外的流感综合征，13%是因为临床状况恶化和死亡。只有7/469名患者患上了COVID-19。与其他年份相比，2020年的放射检查次数显著减少（分别为211次，而2020年、2019年、2018年、2017年和2016年为360次、355次、385次、390次，p < 0.001）。在我们的癌症患者中，COVID-19的发病率很低，加上医院控制感染的政策，使大多数患者获得了安全的癌症治疗和持续的护理，而一小部分患者由于患者相关原因而出现了治疗延迟。
Cancer has been reported as a major risk factor for adverse outcomes and death during COVID-19 pandemic. The aim of this study was to investigate the management of cancer patients and oncological treatments during the COVID-19 pandemic and to describe the containment measures performed in ICS Maugeri outpatient clinic (Pavia, Italy). A comparison with the same period of the four previous years was performed. A significant reduction in access for therapy was seen between the year 2020 and 2019 but not between 2020 and 2018, 2017, or 2016. In 2020, the “pandemic fear” was the most common cause of treatment delay. Only few patients developed COVID-19. A significant reduction in radiological exams was found in 2020 versus all the other years considered. The low incidence of COVID-19 among our cancer patients, along with the hospital policy to control infection, enabled safe cancer treatment and a continuum of care in most patients. Lombardy was the first area in Italy to have an outbreak of coronavirus disease 19 (COVID-19) at the beginning of 2020. In this context, cancer has been reported as a major risk factor for adverse outcomes and death, so oncology societies have quickly released guidelines on cancer care during the pandemic. The aim of this study was to investigate the management of cancer patients and oncological treatments during the COVID-19 pandemic and to describe the containment measures performed in our outpatient clinic at Pavia (Lombardy). A comparison with the same period of the four previous years (2019, 2018, 2017, and 2016) was also performed. Using our electronic databases, we evaluated the number and characteristics of patients accessing the hospital for anticancer drug infusion from 24 February, 2020 to 30 April, 2020 and the number of radiological exams performed. Although a significant reduction in access for therapy was seen when compared with 2019 (2590 versus 2974, access rate ratio (ARR) = 0.85, p < 0.001), no significant differences in access numbers and ARR was evident between 2020 and 2018, 2017, or 2016 (2590 versus 2626 (ARR = 0.07), 2660 (ARR = 0.99), and 2694 (ARR = 0.96), respectively, p > 0.05). In 2020, 63 patients delayed treatment: 38% for “pandemic fear”, 18% for travel restrictions, 13% for quarantine, 18% for flu syndrome other than COVID-19, and 13% for worsening of clinical conditions and death. Only 7/469 patients developed COVID-19. A significant reduction in radiological exams was found in 2020 versus all the other years considered (211 versus 360, 355, 385, 390 for the years 2020, 2019, 2018, 2017, and 2016, respectively, p < 0.001). The low incidence of COVID-19 among our cancer patients, along with the hospital policy to control infection, enabled safe cancer treatment and a continuum of care in most patients, while a small fraction of patients experienced a therapeutic delay due to patient-related reasons.
登录
查看更多内容
影响因子：
5.8
作者：
Viale, Giulia;Licata, Luca;Bianchini, Giampaolo
通讯作者：
Bianchini, Giampaolo
影响因子：
1.8
作者：
Blasi, Livio;Bordonaro, Roberto;Gebbia, Vittorio
通讯作者：
Gebbia, Vittorio
影响因子：
5.2
作者：
Nguyen, Nam P.;Vinh-Hung, Vincent;Thariat, Juliette
通讯作者：
Thariat, Juliette
影响因子：
3.6
作者：
Deckx, Laura;van den Akker, Marjan;Buntinx, Frank
通讯作者：
Buntinx, Frank
影响因子：
3.9
作者：
Curigliano, Giuseppe;Cardoso, Maria Joao;Cardoso, Fatima
通讯作者：
Cardoso, Fatima