SYNTHETIC DERIVATIVES OF POLYETHYLENEIMINE WITH ENZYME-LIKE CATALYTIC ACTIVITY (SYNZYMES)
SYNTHETIC DERIVATIVES OF POLYETHYLENEIMINE WITH ENZYME-LIKE CATALYTIC ACTIVITY (SYNZYMES)
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DOI：
10.1073/pnas.68.2.263
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发表时间：
1971-01-01
影响因子：
11.1
通讯作者：
SCARPA, IS
中科院分区：
文献类型：
--
作者：
KLOTZ, IM;ROYER, GP;SCARPA, IS
A synthetic polymer has been prepared which contains dodecyl groups (to bind small substrate molecules) and methyleneimidazole side chains (as nucleophilic catalytic sites) linked to a polyethyleneimine framework. This macromolecule, with a high local concentration of binding and catalytic groups, catalyzes the hydrolysis ofunchargednitrophenyl esters in water at pH 7 with rates markedly greater than previously observed with any other synthetic substances under similar conditions.
