Outcomes of kidney transplant from deceased donors with acute kidney injury and prolonged cold ischemia time - a retrospective cohort study
Outcomes of kidney transplant from deceased donors with acute kidney injury and prolonged cold ischemia time - a retrospective cohort study
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DOI：
10.1111/tri.13406
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发表时间：
2019-06-01
影响因子：
3.1
通讯作者：
Mohan, Sumit
中科院分区：
文献类型：
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作者：
Dube, Geoffrey K.;Brennan, Corey;Mohan, Sumit
虽然来自具有急性肾损伤（阿基）或长冷缺血时间（CIT）的供体的死亡供体肾移植（DDRT）与移植物功能延迟（DGF）的风险增加相关，但这些肾脏的受体具有良好的患者和同种异体移植物存活率。关于同时存在阿基和长时间CIT的肾脏是否具有与仅存在其中一种损伤的肾脏相似的结局，数据有限。使用来自移植受体科学登记处的数据，我们分析了接受阿基（终末肌酐>= 2.0 mg/dl）和CIT 24-30 h（n = 1289），30-36 h（n = 734）和>36 h（n = 614）肾脏的患者（2005-2015）的移植结局，使用阿基和CIT肾脏
While deceased donor renal transplants (DDRT) from donors with either acute kidney injury (AKI) or long cold ischemia time (CIT) are associated with increased risk of delayed graft function (DGF), recipients of these kidneys have good patient and allograft survival. There are limited data on whether kidneys with both AKI and long CIT have outcomes similar to kidneys with only one of these insults. Using data from the Scientific Registry of Transplant Recipients, we analyzed transplant outcomes in patients (2005-2015) receiving kidneys with AKI (terminal creatinine >= 2.0 mg/dl) and CIT 24-30 h (n = 1289), 30-36 h (n = 734), and >36 h (n = 614), using kidneys with AKI and CIT