Releasing hidden MAMPs from precursor proteins in plants
Releasing hidden MAMPs from precursor proteins in plants
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DOI：
10.1016/j.tplants.2023.09.013
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发表时间：
2024-04-03
影响因子：
20.5
通讯作者：
Buscaill，Pierre
中科院分区：
文献类型：
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作者：
Chen，Changlong;van der Hoorn，Renier A. L.;Buscaill，Pierre
植物在细胞表面识别病原体对于激活植物免疫至关重要。植物利用模式识别受体（PRR）来检测微生物相关分子模式（MAMP）。然而，我们对肽MAMPs从其前体蛋白中释放的知识非常有限。在这里，我们探讨了七个蛋白质前体的知名MAMP肽和讨论的可能性，加工所需的识别基于结构模型和公共知识。该分析表明存在多个细胞外事件，这些事件可能对病原体感知至关重要，但仍有待发现。
The recognition of pathogens by plants at the cell surface is crucial for activating plant immunity. Plants employ pattern recognition receptors (PRRs) to detect microbe-associated molecular patterns (MAMPs). However, our knowledge of the release of peptide MAMPs from their precursor proteins is very limited. Here, we explore seven protein precursors of well-known MAMP peptides and discuss the likelihood of processing being required for their recognition based on structural models and public knowledge. This analysis indicates the existence of multiple extracellular events that are likely pivotal for pathogen perception but remain to be uncovered.