An Efficient Synthesis of Azetidines with (2-Bromoethyl)sulfonium Triflate
An Efficient Synthesis of Azetidines with (2-Bromoethyl)sulfonium Triflate
复制标题
DOI：
10.1055/s-0031-1290951
复制
发表时间：
2012-05-01
影响因子：
2.6
通讯作者：
Aggarwal, Varinder K.
中科院分区：
文献类型：
--
作者：
Fritz, Sven P.;Moya, Juan F.;Aggarwal, Varinder K.
利用市售的（2-溴乙基）三氟甲磺酸锍，将易得的芳基甘氨酸衍生物环化为氮杂环丁烷。高产率反应具有较宽的应用范围，并被推广到氧杂环丁烷的合成。
Easily accessible arylglycine derivatives were cyclized to azetidines by using commercially available (2-bromoethyl)sulfonium triflate in a simple and mild procedure. The high-yielding reaction has a relatively broad scope and was extended to the synthesis of an oxetane.