Systematic identification of tRNA genes in Drosophila melanogaster.
Systematic identification of tRNA genes in Drosophila melanogaster.
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DOI:
10.17912/micropub.biology.000560
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发表时间:
2022
影响因子:
--
通讯作者:
Lowe, Todd M
中科院分区:
文献类型:
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作者:
Marygold, Steven J;Chan, Patricia P;Lowe, Todd M
Transfer RNAs (tRNAs) are ubiquitous adapter molecules that link specific codons in messenger RNA (mRNA) with their corresponding amino acids during protein synthesis. The tRNA genes of Drosophila have been investigated for over half a century but have lacked systematic identification and nomenclature. Here, we review and integrate data within FlyBase and the Genomic tRNA Database (GtRNAdb) to identify the full complement of tRNA genes in the D. melanogaster nuclear and mitochondrial genomes. We apply a logical and informative nomenclature to all tRNA genes, and provide an overview of their characteristics and genomic features.