Graft remodeling and ligamentization after cruciate ligament reconstruction
Graft remodeling and ligamentization after cruciate ligament reconstruction
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DOI：
10.1007/s00167-008-0560-8
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发表时间：
2008-09-01
影响因子：
3.8
通讯作者：
Weiler, A.
中科院分区：
文献类型：
--
作者：
Scheffler, S. U.;Unterhauser, F. N.;Weiler, A.
在重建交叉韧带后，置换移植物必须在关节内移植物区域和移植物-骨结合部位经历几个愈合阶段。在其关节内区域的愈合移植物的生物学和机械性能的变化被描述为韧带化过程。重要的知识已被添加在移植愈合过程中的几个过程的理解，并在这篇文章中进行了总结。了解空间和时间依赖性变化以及不同移植物愈合模型之间的差异对于制定交叉韧带手术治疗方案的改进策略具有重要意义，从而实现完整交叉韧带功能和机械强度的完全恢复。
After reconstruction of the cruciate ligaments, replacement grafts have to undergo several phases of healing in the intra-articular graft region and at the site of graft-to-bone incorporation. The changes in the biological and mechanical properties of the healing graft in its intra-articular region are described as the ligamentization process. Significant knowledge has been added in the understanding of the several processes during the course of graft healing and is summarized in this article. The understanding of the spatial and time-dependent changes as well as the differences between the different models of graft healing are of significant importance to develop strategies of improved treatment options in cruciate ligament surgery, so that full restoration of function and mechanical strength of the intact cruciate ligaments will be achieved.