Estimating dim light melatonin onset (DLMO) phase in adolescents using summer or school-year sleep/wake schedules
Estimating dim light melatonin onset (DLMO) phase in adolescents using summer or school-year sleep/wake schedules
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DOI：
10.1093/sleep/29.12.1632
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发表时间：
2006-12-01
期刊：
影响因子：
5.6
通讯作者：
Carskadon, Mary A.
中科院分区：
文献类型：
--
作者：
Crowley, Stephanie J.;Acebo, Christine;Carskadon, Mary A.
研究目的：这项研究分析了暑假和学年期间儿童和青少年群体的唾液暗淡褪黑素发作(DLMO)时相与自选睡眠/醒来时程之间的关系，以确定睡眠/醒来模式在多大程度上可以预测唾液DLMO时相。设计和地点：受试者连续5个晚上按照自选时刻表在家中睡觉，并通过日常电话消息报告他们的就寝时间和起床时间。每晚每隔30分钟在实验室暗光(<；50lux)下采集唾液褪黑素，以确定DLMO时相。参与者：一组，年龄9-17岁(平均年龄12.5岁，SD=2.3岁，男性74人，女性75人)，其中149人在学年课程表上贡献了DLMO阶段和睡眠/觉醒模式的测量(“学校组”)。另一组9~16岁(平均年龄13.1岁，SD=1.3岁，男性30例，女性29例)在夏季进行DLMO时相和睡眠/觉醒模式的测量(“夏季组”)。尽管暑期组的相关系数均高于学校组，但回归方程预测的DLMO期在测量到的DLMO期后1小时内接近80%。结论：健康儿童和青少年可以在学年或暑假期间使用自己选择的睡眠/觉醒模式来估计DLMO期。
Study Objectives: This analysis examined associations between the salivary dim light melatonin onset (DLMO) phase and self-selected sleep/wake schedules in groups of children and adolescents during summer vacation and during the school year to determine the degree to which sleep/wake patterns can estimate salivary DLMO phase.Design And Setting: Participants slept at home on self-selected schedules for 5 consecutive nights and reported their bedtime and wake-up time via daily telephone messages. Salivary melatonin was sampled in the laboratory on one evening every 30 minutes in dim light (< 50 lux) to determine DLMO phase. Within group bivariate regressions between sleep pattern measures (bedtime, wake-up time, and midsleep time) and DLMO phase were computed.Participants: One group, ages 9 to 17 years (mean age = 12.5, SD = 2.3 years, 74 males, 75 females) contributed 149 DLMO phase and sleep/wake pattern measures while on a school year schedule ("school group"). A separate group, ages 9 to 16 years (mean age = 13.1, SD = 1.3 years, 30 males, 29 females) contributed 59 DLMO phase and sleep/wake pattern measures while on a summer schedule ("summer group").Results: Bedtime, midsleep time, and wake-up time were positively correlated with DLMO phase in both groups. Although all correlation coefficients for the summer group were statistically greater compared to the school group, the regression equations predicted DLMO phase within 1 hour of the measured DLMO phase in similar to 80% for both groups.Conclusions: DLMO phase can be estimated using self-selected sleep/wake patterns during the school year or summer vacation in healthy children and adolescents.