Blood flow in intestinal absorption models
Blood flow in intestinal absorption models
复制标题
肠道吸收模型中的血流
DOI：
10.1007/bf01066063
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发表时间：
1978
期刊：
影响因子：
--
通讯作者：
D. Winne
中科院分区：
文献类型：
--
作者：
D. Winne
迄今为止，已经提出或应用了十种模型来分析血流与肠道吸收之间的关系。描述了这些模型的概念及其基本和最终方程。此外，还阐明了它们与未明确包括血流速率的模型中使用的一阶速率常数的关系。通常，模型预测血流量和吸收率之间的曲线（凹曲率）关系。曲线的这种相似性是在许多情况下多个模型与实验数据兼容的原因。
Up to the present, ten models have been proposed or applied to analyze the relationship between blood flow and intestinal absorption. The conceptions of these models and their basic and final equations are described. In addition, their relationship to the first-order rate constants used in the models not explicitly including the blood flow rate is elucidated. Usually a curvilinear (concave curvature) relationship between the blood flow rate and the absorption rate is predicted by the models. This similarity of the curves is the reason that in many cases several models are compatible with the experimental data.