METLIN - A metabolite mass spectral database
METLIN - A metabolite mass spectral database
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DOI：
10.1097/01.ftd.0000179845.53213.39
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发表时间：
2005-12-01
影响因子：
2.5
通讯作者：
Siuzdak, G
中科院分区：
文献类型：
--
作者：
Smith, CA;O'Maille, G;Siuzdak, G
内源性代谢物在过去的5年中获得了越来越多的关注，主要是因为它们在诊断和药物生物标志物发现中的意义。METLIN（http：//metlin. scripps.edu），这是一个可免费访问的网络数据储存库，旨在协助开展广泛的代谢物研究，并通过质量分析促进代谢物的鉴定。METLIN包括已知代谢物结构信息的注释列表，这些信息很容易与其高分辨率傅里叶变换质谱（FTMS）光谱、串联质谱（MS/MS）光谱和LC/MS数据目录交叉相关。
Endogenous metabolites have gained increasing interest over the past 5 years largely for their implications in diagnostic and pharmaceutical biomarker discovery. METLIN (http://metlin. scripps.edu), a freely accessible web-based data repository, has been developed to assist in a broad array of metabolite research and to facilitate metabolite identification through mass analysis. METLIN includes an annotated list of known metabolite structural information that is easily cross-correlated with its catalogue of high-resolution Fourier transform mass spectrometry (FTMS) spectra, tandem mass spectrometry (MS/MS) spectra, and LC/MS data.