Spectrum of T2*values in knee joint cartilage at 3 T: a cross-sectional analysis in asymptomatic young adult volunteers
Spectrum of T2*values in knee joint cartilage at 3 T: a cross-sectional analysis in asymptomatic young adult volunteers
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DOI：
10.1007/s00256-013-1806-1
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发表时间：
2014-04-01
影响因子：
2.1
通讯作者：
Zilkens, Christoph
中科院分区：
文献类型：
--
作者：
Bittersohl, Bernd;Hosalkar, Harish S.;Zilkens, Christoph
为了建立健康膝关节软骨在3T的基线T2*值。34名志愿者(平均年龄：24.6+/-2.7岁)没有任何膝关节疾病的病史或临床表现。该方案包括用于形态软骨评估的双回波稳态(DESS)序列和用于T2*评估的梯度回波多回波序列。测量了8个区域的T2*值：股骨后外侧、股骨中央外侧、滑车、膝盖骨、胫骨外侧平台、股骨后内侧平台、股骨中央内侧平台和胫骨内侧平台。统计学评价包括双尾t检验和单因素方差分析，以确定地区和地区的差异。T2*标测显示除股骨内侧后髁外，所有地区的浅层T2*值都较高(P值为千分之0.001欧元)(P=0.087)，显著的地区差异显示滑车软骨的T2*值较高，髌骨和股骨中央髁软骨的T2*值较高，股骨后髁软骨和胫骨平台软骨的T2*值较低。在进行膝关节软骨T2*标测时，应考虑T2*测量的区域差异。
To establish baseline T2* values in healthy knee joint cartilage at 3 T.Thirty-four volunteers (mean age: 24.6 +/- 2.7 years) with no history or clinical findings indicative of any knee joint disease were enrolled. The protocol included a double-echo steady-state (DESS) sequence for morphological cartilage evaluation and a gradient-echo multi-echo sequence for T2* assessment. Bulk and zonal T2* values were assessed in eight regions: posterior lateral femoral condyle; central lateral femoral condyle; trochlea; patella; lateral tibial plateau; posterior medial femoral condyle; central medial femoral condyle; and medial tibial plateau. Statistical evaluation comprised a two-tailed t test and a one-way analysis of variance to identify zonal and regional differences.T2* mapping revealed higher T2* values in the superficial zone in all regions (P values a parts per thousand currency signaEuro parts per thousand 0.001) except for the posterior medial femur condyle (P = 0.087), and substantial regional differences demonstrating superior values in trochlear cartilage, intermediate values in patellar and central femoral condylar cartilage, and low T2* values in posterior femoral condylar cartilage and tibial plateau cartilage.Substantial regional differences in T2* measures should be taken into consideration when conducting T2* mapping of knee joint cartilage.