Grading cervical cord damage in neuromyelitis optica and MS by diffusion tensor MRI

Grading cervical cord damage in neuromyelitis optica and MS by diffusion tensor MRI
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DOI:
10.1212/01.wnl.0000223637.65208.7c
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发表时间:
2006-07-11
期刊:
影响因子:
9.9
通讯作者:
Filippi, M.
Filippi, M.
中科院分区:
医学1区
文献类型:
--
作者:
Benedetti, B.;Valsasina, P.;Filippi, M.

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作者评估了扩散张量MRI对10例视神经肌萎缩症患者、10例多发性硬化症患者和10例健康对照者的颈髓损伤进行分级的能力。三组在平均扩散率(p = 0.008)和平均各向异性分数(p = 0.04)方面存在差异。扩展标准残疾状态量表评分和脊髓平均扩散率之间存在相关性(r = 0.52,p = 0.02)。
The authors assessed the ability of diffusion tensor MRI to grade cervical cord damage in 10 patients with neuromyelitis optica, 10 patients with multiple sclerosis, and 10 healthy controls. The three groups differed in terms of average mean diffusivity (p = 0.008) and average fractional anisotropy (p = 0.04). There was a correlation between the Expanded Standard Disability Status Scale score and cord average mean diffusivity (r = 0.52, p = 0.02).