Pain and health-related quality of life in people with chronic leg ulcers.
Pain and health-related quality of life in people with chronic leg ulcers.
复制标题
慢性腿部溃疡患者的疼痛和与健康相关的生活质量。
DOI：
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复制
发表时间：
2013
影响因子：
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通讯作者：
M. Harrison
中科院分区：
文献类型：
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作者：
W. Hopman;W. Hopman;M. Buchanan;E. Vandenkerkhof;M. Harrison
介绍
下肢静脉溃疡与疼痛和健康相关生活质量（HRQL）差相关。本研究的目的是确定与活动性静脉溃疡患者疼痛和HRQL降低相关的人口统计学和临床特征。
方法
基线数据来自2001年至2007年期间进行的两项试验（n = 564）。使用数字疼痛量表（Numeric Pain Scale）测量疼痛，使用医学结局调查12项简表（SF-12）测量HRQL，该量表生成身体（PCS）和精神健康总评（MCS）。分析包括logistic和线性回归（分别针对疼痛和HRQL）。
结果
平均年龄为66.5岁; 47%为男性。中位HRQL评分为2.2（满分10分），平均PCS和MCS评分分别为38.0和50.5（评分标准化为平均50分，代表平均HRQL）。年轻、与他人同住和关节炎与疼痛有关。Popletin PCS与女性、静脉性/混合性溃疡病因、较大溃疡、较长溃疡持续时间、心血管疾病、关节炎和较高疼痛强度相关。溃疡性结肠炎与年龄较小、溃疡持续时间较长、合并症和疼痛强度较高相关。
结论
需要进行研究来测试减少疼痛的策略，并可能改善高危人群的HRQL。
INTRODUCTION
Venous leg ulceration is associated with pain and poor health-related quality of life (HRQL). The purpose of this study was to identify demographic and clinical characteristics associated with pain and decreased HRQL in patients with active venous ulcers.
METHODS
Baseline data were combined from two trials that took place between 2001 and 2007 (n = 564). Pain was measured using the Numeric Pain Scale (NPS), and HRQL was measured using the Medical Outcomes Survey 12-item Short Form (SF-12), which generates a Physical (PCS) and Mental Component Summary (MCS). Analyses included logistic and linear regression (for pain and HRQL, respectively).
RESULTS
Mean age was 66.5 years; 47% were male. Median NPS score was 2.2 (out of 10) and mean PCS and MCS scores were 38.0 and 50.5, respectively (scores are standardized to a mean of 50 representing average HRQL). Younger age, living with others, and arthritis were associated with pain. Poorer PCS was associated with being female, venous/mixed ulcer etiology, larger ulcers, longer ulcer duration, cardiovascular disease, arthritis and higher pain intensity. Poorer MCS was associated with younger age, longer ulcer duration, comorbidity and higher pain intensity.
CONCLUSION
Research is needed to test strategies to reduce pain and possibly improve HRQL in high risk groups.