Thrombosis on a mechanical mitral valve anticoagulated with dabigatran

Thrombosis on a mechanical mitral valve anticoagulated with dabigatran
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达比加群抗凝机械二尖瓣血栓形成

DOI:
10.1007/s11239-013-0935-7
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发表时间:
2013
影响因子:
4
通讯作者:
Karla Campos
Karla Campos
中科院分区:
医学4区
文献类型:
--
作者:
S. Coulter;Karla Campos

文献摘要

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机械心脏瓣膜的血栓形成是危及生命的。瓣膜血栓形成的总体风险较低,年风险为0.2- 0.4%[1]。二尖瓣位置的机械瓣膜的血栓形成风险(1.0- 3.8%)高于主动脉位置的机械瓣膜(0.1- 0.6%)[2,3]。终身口服抗凝治疗对于预防机械心脏瓣膜植入后的血栓栓塞事件至关重要。
Thrombosis of a mechanical heart valve is life-threatening. The overall risk of valve thrombosis is low, with an annual risk of 0.2–0.4 % [1]. Mechanical valves in the mitral position are at a greater risk of thrombosis (1.0–3.8 %) than those placed in the aortic position (0.1–0.6 %) [2, 3]. Lifelong oral anticoagulation therapy is essential for preventing thromboembolic events after implantation of a mechanical heart valve.