EFFECTS OF MARIJUANA ON TESTOSTERONE IN MALE-SUBJECTS
EFFECTS OF MARIJUANA ON TESTOSTERONE IN MALE-SUBJECTS
复制标题
DOI：
10.1016/0022-5193(83)90255-2
复制
发表时间：
1983-01-01
影响因子：
2
通讯作者：
LICKO, V
中科院分区：
文献类型：
--
作者：
BARNETT, G;CHIANG, CWN;LICKO, V
Clinical studies given contradictory reports on the effect of smoking marihuana on the plasma levels of testosterone in males. A reanalysis of existing data established that testosterone levels are depressed both after smoking 1 marihuana cigarette and after i.v. infusion of .DELTA.-9-tetrahydrocannabinol, a pharmacologically active component of marihuana. Simulation of the marihuana interaction, under the assumption that .DELTA.-9-tetrahydrocannabinol inhibits testosterone production or secretion, suggests a minimum of 24 h are required for testosterone to return to pre-smoking levels. A series of clinical studies are specified to clarify the nature of the interaction.
