[Age-related macular degeneration].
[Age-related macular degeneration].
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DOI：
10.1056/nejmc081470
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发表时间：
2006
影响因子：
--
通讯作者：
A. Ramé
中科院分区：
文献类型：
--
作者：
A. Ramé
年龄相关性黄斑变性主要影响中央视力，而中央视力是阅读、驾驶和识别面部等详细任务所必需的。这种情况下的视力丧失是由于眼睛后部检测光线和颜色的组织（视网膜）中的感光细胞逐渐退化所致。具体来说，与年龄相关的黄斑变性会影响视网膜中心附近的一个小区域，称为黄斑，负责中央视力。侧视（周边）视力和夜视一般不受影响，但在疾病早期经常出现视力对黑暗的缓慢调整（暗适应）和弱光（暗视）视力下降。
Age-related macular degeneration mainly affects central vision, which is needed for detailed tasks such as reading, driving, and recognizing faces. The vision loss in this condition results from a gradual deterioration of light-sensing cells in the tissue at the back of the eye that detects light and color (the retina). Specifically, age-related macular degeneration affects a small area near the center of the retina, called the macula, which is responsible for central vision. Side (peripheral) vision and night vision are generally not affected, but slow adjustment of vision to darkness (dark adaptation) and reduced dim light (scotopic) vision often occur in the early stages of the disease.