PROLONGED ATRIAL CONDUCTION - MAJOR PREDISPOSING FACTOR FOR DEVELOPMENT OF ATRIAL-FLUTTER
PROLONGED ATRIAL CONDUCTION - MAJOR PREDISPOSING FACTOR FOR DEVELOPMENT OF ATRIAL-FLUTTER
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DOI：
10.1161/01.cir.57.2.213
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发表时间：
1978-01-01
期刊：
影响因子：
37.8
通讯作者：
SCHAAL, SF
中科院分区：
文献类型：
--
作者：
LEIER, CV;MEACHAM, JA;SCHAAL, SF
对 21 名证明自发发生持续性心房扑动的患者进行了窦性心律期间的电生理学研究，以确定心房传导疾病是否是心房扑动发生的诱发因素。心房扩大的患者被排除在该系列之外。对照组由 11 名年龄匹配且心电图和电生理学研究正常的患者组成。扑动组的平均右心房传导时间延长为 50 ms（对照为 37 ms，P < 0.05），平均心房传导时间延长为 92 ms（对照为 44 ms，P < 0.001），平均 P 波持续时间延长为 132 ms（对照为 112 ms，P < 0.01）。与对照组相比，扑动组窦房结功能障碍和心室传导疾病的发生率更高。发生心房扑动的患者可能患有心房传导疾病。心房传导疾病似乎是心房扑动发生的主要诱发因素，也是纤维退行性传导疾病谱系的一部分。
Electrophysiological studies were performed during sinus rhythm on 21 patients who demonstrated the spontaneous occurrence of sustained atrial flutter, to determine if atrial conduction disease is a predisposing factor for the development of atrial flutter. Patients with atrial enlargement were excluded from the series. The control group consisted of 11 age-matched patients with normal ECG and electrophysiology studies. The flutter group showed prolongation of the mean right intra-atrial conduction time at 50 ms (control of 37 ms, P < 0.05), the mean interatrial conduction time at 92 ms (control of 44 ms, P < 0.001) and the mean P wave duration at 132 ms (control of 112 ms, P < 0.01). The flutter group demonstrated a higher incidence of sinus node dysfunction and ventricular conduction disease compared to the control group. Patients who develop atrial flutter may have atrial conduction disease. Atrial conduction disease appears to be a major predisposing factor for the development of atrial flutter and a part of the fibro-degenerative conduction disease spectrum.