Comparative trial of nortriptyline and amitriptyline in 100 depressed patients.
Comparative trial of nortriptyline and amitriptyline in 100 depressed patients.
复制标题
去甲替林和阿米替林在 100 名抑郁症患者中的比较试验。
DOI：
10.1176/ajp.124.8s.59
复制
发表时间：
1968
期刊：
影响因子：
--
通讯作者：
J. Mendels
中科院分区：
文献类型：
--
作者：
J. Mendels
对100名使用阿米替林及其衍生物去甲替林的抑郁症患者进行了双盲试验。在汉密尔顿抑郁量表上获得的分数被用作变化指数。用去甲替林治疗的患者比用阿米替林治疗的患者反应明显更快，但在治疗六周后，两种药物的反应没有差异。
A double-blind trial was conducted on 100 depressed patients using amitriptyline and its derivative, nortriptyline. Scores obtained on the Hamilton Depression Scale were used as an index of change. Patients treated with nortriptyline responded significantly more rapidly than patients treated with amitriptyline, but there was no difference in response to the two drugs after six weeks of treatment.