Quality of life, self-esteem and worries in young adult survivors of childhood cancer
Quality of life, self-esteem and worries in young adult survivors of childhood cancer
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DOI：
10.1002/pon.800
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发表时间：
2004-12-01
期刊：
影响因子：
3.6
通讯作者：
Van Den Bos, C
中科院分区：
文献类型：
--
作者：
Langeveld, NE;Grootenhuis, MA;Van Den Bos, C
这项研究评估了儿童癌症年轻幸存者与一组没有癌症病史的年轻人的生活质量、自尊和担忧。研究了人口、医疗和治疗因素以及自尊对幸存者生活质量和担忧的影响。参与者包括平均 16 年前完成治疗的 400 名儿童癌症长期幸存者 (LTS)（年龄范围 16-49 岁，45% 女性）和 560 名没有癌症病史的人（年龄范围 16-53 岁，55% 女性）。所有参与者都完成了 MOS-24（医疗结果研究量表），这是一份忧虑问卷，由三个量表组成（癌症特定问题、一般健康问题、现在和未来的问题）。 LTS 组和对照组之间的平均 MOS-24 分数存在小到中度差异（范围效应大小 -0.36-0.22）。 LTS 和对照组之间的平均自尊得分没有显着差异。女性 LTS 比男性 LTS 有更多癌症特异性的担忧。在一般健康、自我形象和死亡等几个相关领域，LTS 组的担忧少于对照组，但 LTS 组更担心自己的生育能力、获得/换工作和获得保险。多元线性回归分析显示，女性、失业、严重的迟发效应/健康问题和自尊心低下是幸存者生活质量较差的预测因素。此外，随访年龄、失业、完成治疗的年数和自尊心低下与幸存者的担忧程度较高有关。儿童癌症 LTS 的生活质量和自尊水平与同龄人没有什么不同。尽管许多长期支持者对健康问题的担忧并不比同龄人多，甚至更少，但他们常常担心一些当前和未来的问题。所调查的因素只能在有限程度上解释生活质量差和担忧。有必要进一步研究探索 LTS 生活质量和忧虑的决定因素和指数。版权所有 (C) 2004 John Wiley Sons, Ltd.
This study assessed quality of life, self-esteem and worries in young adult survivors of childhood cancer compared to a group of young adults with no history of cancer. The impact of demographic, medical and treatment factors and self-esteem on survivors' quality of life and worries was studied.Participants were 400 long-term survivors (LTS) of childhood cancer (age range 16-49 years, 45% female) who had completed treatment an average of 16 years previously and 560 persons (age range 16-53 years, 55% female) with no history of cancer. All participants completed the MOS-24 (Medical Outcome Study Scale), a Worry questionnaire consisting of three scales (cancer-specific concerns, general health concerns, present and future concerns). and the Rosenberg Self-Esteem Scale.Small to moderate differences were found in mean MOS-24 scores between the LTS group and controls (range effect sizes -0.36-0.22). No significant difference was found in the mean self-esteem scores between LTS and controls. Female LTS had more cancer-specific concerns than male LTS. In several related areas of general health, self-image and dying, the LTS group reported less worries than controls, but LTS worried significantly more about their fertility, getting/changing a job and obtaining insurance's. Multiple linear regression analysis revealed that female gender, unemployment, severe late effects/health problems and a low self-esteem were predictors of worse quality of life in survivors. In addition, age at follow-up, unemployment, years since completion of therapy and a low self-esteem were associated with a higher degree of survivors' worries.Quality of life and the level of self-esteem in LTS of childhood cancer is not different from their peers. Although many LTS worried not more or even less about health issues than their peers, they often are concerned about some present and future concerns. The investigated factors could explain poor quality of life and worries only to a limited extent. Further research exploring determinants and indices of quality of life and worries in LTS is warranted. Copyright (C) 2004 John Wiley Sons, Ltd.