Biomagnetic detection of gastric electrical activity in normal and vagotomized rabbits
Biomagnetic detection of gastric electrical activity in normal and vagotomized rabbits
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DOI：
10.1046/j.1365-2982.2003.00432.x
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发表时间：
2003-10-01
影响因子：
3.5
通讯作者：
Richards, WO
中科院分区：
文献类型：
--
作者：
Bradshaw, LA;Myers, AG;Richards, WO
本文用超导量子干涉仪（SQUID）记录了正常家兔胃电活动（GEA）引起的胃磁矢量图（MGG），并测量了MGG与24通道Serenogram电极的相关程度。矢量磁力仪允许我们非侵入性地记录三个正交磁场分量，并将记录的磁场矢量投影到任意方向。我们优化了磁场矢量方向，以获得与每个伺服电极记录的最高可能相关性。我们进行了迷走神经切断术，并检查了空间和时间的变化，在serovirus电位和经腹磁场。我们通过将记录的信号映射到胃肌肉组织中的电极位置来获得空间信息。时间上的解耦的证据，观察到在光谱分析的Serenium电极和SQUID磁强计记录。我们的结论是，非侵入性记录的向量胃磁图反映潜在的seroviral电位以及迷走神经切断术后的病理生理变化。
We recorded the vector magnetogastrogram (MGG) due to gastric electrical activity (GEA) in normal rabbits using a Superconducting QUantum Interference Device (SQUID) magnetometer and measured the degree of correlation of the MGG with 24 channels of serosal electrodes. The vector magnetometer allows us to non-invasively record three orthogonal magnetic field components and project the recorded magnetic field vector into arbitrary directions. We optimized the magnetic field vector direction to obtain the highest possible correlation with each serosal electrode recording. We performed a vagotomy and examined spatial and temporal changes in the serosal potential and in the transabdominal magnetic field. We obtained spatial information by mapping the recorded signals to the electrode positions in the gastric musculature. Temporal evidence of uncoupling was observed in spectral analyses of both serosal electrode and SQUID magnetometer recordings. We conclude that non-invasive recordings of the vector magnetogastrogram reflect underlying serosal potentials as well as pathophysiological changes following vagotomy.