Prevalence of congenital malaria in Ile-Ife, Nigeria
Prevalence of congenital malaria in Ile-Ife, Nigeria
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DOI：
10.1093/tropej/fmi003
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发表时间：
2005-08-01
影响因子：
2
通讯作者：
Adeodu, OO
中科院分区：
文献类型：
--
作者：
Obiajunwa, PO;Owa, JA;Adeodu, OO
该研究旨在确定先天性疟疾、脐带血和胎盘疟原虫血症的患病率以及先天性疟疾临床表现的患病率。伊费岛是疟疾大流行区。对 120 名新生儿的胎盘、脐带和外周血涂片进行了疟疾寄生虫检查。其中包括 104 名（86.7%）足月婴儿和 16 名（13.3%）早产儿。在 56 例（46.7%）外周血涂片、68 例（56.7%）胎盘和 65 例（54.2%）脐带血涂片中分别发现寄生虫血症阳性。胎盘疟疾、脐带疟原虫血症和先天性疟疾之间存在很强的相关性（p < 0.001）。先天性疟疾在伊费岛的发病率很高。新生儿的临床表现很少。只有两名婴儿在出生后 48 小时内发烧。
The study was designed to determine the prevalence of congenital malaria, cord blood and placental malaria parasitaemia and the prevalence of clinical manifestations of congenital malaria. Ile-Ife is a holoendemic area for malaria. Placental, cord and peripheral blood smears of 120 newborn babies were examined for malaria parasites. They consisted of 104 (86.7 per cent) full term babies and 16 (13.3 per cent) preterm babies. Positive parasitaemia was found in 56 (46.7 per cent) of peripheral blood smears, 68 (56.7 per cent) and 65 (54.2 per cent) of the placental and cord blood smears respectively. There were strong associations between placental malaria and cord malaria parasitaemia and congenital malaria (p < 0.001). Congenital malaria has a high prevalence in Ile-Ife. There is a paucity of its clinical manifestations in the newborn. Only two babies had fever within 48 hours of birth.