Is the hippocampus involved in temporal discrimination and the memory of short intervals?
Is the hippocampus involved in temporal discrimination and the memory of short intervals?
复制标题
海马体是否参与时间辨别和短间隔记忆？
DOI：
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发表时间：
1997
影响因子：
2.2
通讯作者：
B. N. Bunnell
中科院分区：
文献类型：
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作者：
Arne Dietrich;Joseph D. Allen;B. N. Bunnell
对海马体和下托损伤的大鼠进行计时行为和时间记忆测试。使用峰值程序，他们接受训练以区分 40 秒的间隔，并通过保留间隙测试时间记忆。结果是在内部时钟的理论框架内并根据当前的海马功能理论进行解释的。计时行为不受任何病变的影响，并且没有观察到时间辨别功能的变化。病变也未能表现出对时间事件的记忆缺陷。对于所有组，保留间隙使平均峰值时间增加了间隙时间。这表明所有大鼠都使用了需要使用工作记忆的停止规则。因此，得出的结论是，海马体对于准确的计时行为和时间事件的记忆都不是必需的。
Rats with lesions to the hippocampus proper and the subiculum were tested for timing behavior and temporal memory. Using the peak procedure, they were trained to discriminate a 40 s interval and a retention gap tested the memory for time. Results were interpreted within the theoretical framework of the internal clock and with respect to current theories on hippocampal function. Timing behavior was unaffected by either lesion and no shifts in the temporal discrimination functions were observed. The lesions also failed to show a deficit in the memory for temporal events. For all groups, the retention gap increased the mean peak time by the time of the gap. This indicated that all rats used the stop rule which required the use of working memory. Thus, it was concluded that the hippocampus is neither necessary for accurate timing behavior nor for the memory of temporal events.
内部时钟标准的反馈控制需要海马功能。
影响因子：
1.9
作者：
Meck,WH
通讯作者：
Meck,WH