ANTIBODY SYNTHESIS AT CELLULAR LEVEL - ANTIBODY-INDUCED SUPPRESSION OF 7S ANTIBODY SYNTHESIS
ANTIBODY SYNTHESIS AT CELLULAR LEVEL - ANTIBODY-INDUCED SUPPRESSION OF 7S ANTIBODY SYNTHESIS
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DOI：
10.1084/jem.124.5.953
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发表时间：
1966-01-01
影响因子：
15.3
通讯作者：
WIGZELL, H
中科院分区：
文献类型：
--
作者：
WIGZELL, H
细胞和血清水平的溶血--静脉内接种4 × 105绵羊红细胞可引起直接和间接溶血空斑形成细胞（PFC），如图1所示。当接种鸡红细胞时，得到类似的图。脾中直接溶血空斑形成细胞的数量在抗原给药后第4 - 5天左右达到峰值，随后迅速下降。发现19 S血清滴度与直接空斑形成细胞的数量平行
RESULTSI~ ir~ t Hemolysis at the Cellular and Serum LeveL--The inoculation of 4 X l0 s sheep red blood cells intravenously cause direct and indirect hemolytic plaque-forming cells (PFC) to appear as shown in Fig. 1. A similar figure was obtained when chicken red blood cells were inoculated. The number of direct hemolytic plaque-forming cells in the spleen reached the peak around day 4 to 5 after antigen administration followed by a rapid decrease. The 19S serum titers were found to run parallel to the number of direct plaque-forming cells