Behavioral and clinical factors associated with depression among individuals with diabetes

Behavioral and clinical factors associated with depression among individuals with diabetes
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DOI:
10.2337/diacare.27.4.914
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发表时间:
2004-04-01
期刊:
影响因子:
16.2
通讯作者:
Young, B
Young, B
中科院分区:
医学1区
文献类型:
--
作者:
Katon, W;Von Korff, M;Young, B

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目的 - 本研究的目的是在控制潜在的混杂变量后,确定与抑郁症相关的糖尿病的行为和临床特征。 研究设计和方法 - 向来自健康维护组织的九个初级保健诊所的糖尿病患者发送了一项基于人群的邮件调查。使用患者健康问卷来诊断抑郁症,并使用自动诊断、药学和实验室数据来测量糖尿病治疗强度、HbA(1c) 水平和糖尿病并发症。 结果 - 与符合重度抑郁症标准的可能性显着较高相关的独立因素包括年龄较小、女性、受教育程度较低、未婚、BMI 大于或等于 30 kg/m(2)、吸烟、非糖尿病合并症较高、糖尿病并发症数量较多男性、胰岛素治疗和患者 HbA(1c) 水平升高
OBJECTIVE - The goal of this study was to determine the behavioral and clinical characteristics of diabetes that are associated with depression after controlling for potentially confounding variables.RESEARCH DESIGN AND METHODS - A population-based mail survey was sent to patients With diabetes from nine primary care clinics of a health maintenance organization. The Patient Health Questionnaire was used to diagnose depression, and automated diagnostic, pharmacy, and laboratory data were used to measure diabetes treatment intensity, HbA(1c) levels, and diabetes complications.RESULTS - independent factors that were associated with a significantly higher likelihood of meeting criteria for major depression included younger age, female sex, less education, being unmarried, BMI greater than or equal to 30 kg/m(2), smoking, higher nondiabetic medical comorbidity, higher numbers of diabetes complications in men, treatment with insulin, and higher HbA(1c) levels in patients