Depression in Frontotemporal Dementia
Depression in Frontotemporal Dementia
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DOI：
10.1176/appi.psy.50.3.239
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发表时间：
2009-05-01
期刊：
影响因子：
3.4
通讯作者：
Rabins, Peter V.
中科院分区：
文献类型：
--
作者：
Blass, David M.;Rabins, Peter V.
目的：作者描述了一系列额颞叶痴呆（FTD）患者的情绪异常。方法：作者对FTD患者的门诊和住院病历进行了结构化回顾。结果：三个不同的抑郁症被确定：第一个对应于DSM-IV抑郁症。第二种是情绪不稳定综合征，对环境的反应突出。第三种是极度冷漠的综合征，没有其他抑郁症的证据。结论：多种情绪障碍见于FTD，需要仔细注意鉴别诊断。在评价情绪异常老年患者期间，FTD应纳入鉴别诊断。（Psychosomatics 2009; 50：239-247）
Objective: The authors describe mood abnormalities seen in a case series of patients with frontotemporal dementia (FTD). Method: Authors provide a structured review of outpatient and inpatient charts of FTD patients. Results: Three distinct depressive syndromes were identified: The first corresponds to DSM-IV major depression. The second is a syndrome of mood lability with prominent responsiveness to the environment. The third is a syndrome of profound apathy, without other evidence of depression. Conclusion: A variety of mood disorders are seen in FTD, requiring careful attention to differential diagnosis. FTD should be included in the differential diagnosis during the evaluation of older patients with mood abnormalities. (Psychosomatics 2009; 50: 239-247)