Involvement of medial temporal structures in reflexive attentional shift by gaze
Involvement of medial temporal structures in reflexive attentional shift by gaze
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DOI：
10.1093/scan/nsm027
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发表时间：
2008-03-01
影响因子：
4.2
通讯作者：
Toichi, Motomi
中科院分区：
文献类型：
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作者：
Okada, Takashi;Sato, Wataru;Toichi, Motomi
最近的研究表明，即使眼睛注视不能预测环境中的任何事件，也会触发观察者视觉空间注意力的反射性转移。为了确定内侧颞叶结构是否参与这种反射性凝视处理，我们在七名接受过单侧颞叶切除术的癫痫患者和九名年龄和智商匹配的未接受任何手术治疗的癫痫对照者中进行了凝视提示范例实验。目光线索被呈现到单侧视野 200 毫秒，之后要求受试者尽快定位目标。他们还被告知凝视方向并不能预测目标的位置。当凝视线索刺激脑叶切除患者的完整半球或对照组的任一半球时，当凝视方向朝向目标而不是远离目标时，正确反应的反应时间明显更短。在脑叶切除患者的病变半球受到刺激后，这种提示效应并未显现出来。这些发现表明，包括杏仁核在内的内侧颞叶结构在人类由他人注视方向引发的反射性注意力转移中发挥着至关重要的作用。
Recent studies have revealed that eye gaze triggers reflexive shift of the observers visuospatial attention to its direction even if it does not predict any events in the environment. To determine whether medial temporal structures are involved in this reflexive gaze processing, an experiment of the gaze-cuing paradigm was carried out in seven epileptic patients who had undergone unilateral temporal lobectomy and nine age- and IQ-matched epileptic controls who had not undergone any surgical treatments. Gaze cues were presented for 200ms to the unilateral visual field, after which subjects were required to localize targets as quickly as possible. They were also instructed that gaze directions were not predictive of the location of the targets. When the gaze cues stimulated the intact hemisphere in lobectomized patients or either hemisphere in controls, reaction times for correct responses were significantly shorter when gaze directions were toward the targets than away from the targets. This cuing effect was not manifested following stimulation of the lesioned hemisphere in lobectomized patients. These findings suggest that the medial temporal structures, including the amygdala, play a crucial role in the reflexive shift of attention triggered by another persons gaze direction in humans.