Efficacy of electrical stimulation and exercise for dysphagia in patients with head and neck cancer: A randomized clinical trial
Efficacy of electrical stimulation and exercise for dysphagia in patients with head and neck cancer: A randomized clinical trial
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DOI：
10.1002/hed.24197
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发表时间：
2016-04-01
影响因子：
2.9
通讯作者：
Doros, Gheorghe
中科院分区：
文献类型：
--
作者：
Langmore, Susan E.;McCulloch, Timothy M.;Doros, Gheorghe
背景。神经肌肉电刺激 (NMES) 是一种备受追捧但研究很少的治疗头颈癌吞咽困难患者吞咽困难的方法。本研究调查了 NMES 在此患者群体中的疗效。方法。在这项双盲、随机对照试验中，170 名治疗后出现吞咽困难的头颈癌患者被随机分为主动 NMES+ 吞咽运动组和假 NMES+ 吞咽运动组。 12 周计划后的结果包括透视测量、饮食和生活质量的变化。结果。 12 周计划结束后，活跃 NMES 组的穿透渴望量表得分明显低于假手术组。两组的饮食和生活质量均显着改善。没有其他措施是显着的。结论。 NMES 并没有给传统的吞咽练习带来好处。不幸的是，吞咽练习本身也没有效果。对于因放射治疗引起中度至重度吞咽困难的头颈癌患者，目前的行为疗法对逆转长期吞咽困难的帮助有限。 (C) 2015 年 Wiley 期刊，
Background. Neuromuscular electrical stimulation (NMES) is a highly sought after but poorly studied treatment for dysphagia among patients with head and neck cancer with dysphagia. This study investigated the efficacy of NMES in this patient population.Methods. In this double-blinded, randomized controlled trial, 170 patients with head and neck cancer experiencing posttreatment dysphagia were randomized into active NMES+swallow exercise versus sham NMES+swallow exercise groups. Outcomes after a 12-week program included changes in fluoroscopy measures, diet, and quality of life.Results. After the 12-week program, the active NMES group had significantly worse Penetration Aspiration Scale scores than the sham group. Both groups reported significantly better diet and quality of life. No other measures were significant.Conclusion. NMES did not add benefit to traditional swallow exercises. Unfortunately, swallow exercises were not effective by themselves either. For patients with head and neck cancer with moderate to severe dysphagia caused by radiation therapy, current behavioral therapies are of limited help in reversing long-term dysphagia. (C) 2015 Wiley Periodicals,