Prevention of Bronchopulmonary Dysplasia: A Summary of Evidence-Based Strategies.

Prevention of Bronchopulmonary Dysplasia: A Summary of Evidence-Based Strategies.
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DOI:
10.1542/neo.20-4-e189
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发表时间:
2019-04-01
期刊:
影响因子:
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通讯作者:
Jensen, Erik A
Jensen, Erik A
中科院分区:
其他
文献类型:
--
作者:
Jensen, Erik A

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支气管肺发育不良(BPD)是极早产儿最常见的慢性并发症。虽然BPD现在在出生体重高于1500克的婴儿中并不常见,但在出生时达到或接近目前生存能力极限的婴儿中,BPD的发病率在过去的二三十年中没有改善,而且可能会增加。没有单一的治疗干预措施能有效预防BPD。因此,临床医生必须采用多种循证策略来帮助降低BPD发病率。本文综述了目前预防BPD的循证方法,主要关注随机对照试验的数据。
Bronchopulmonary dysplasia (BPD) is the most common chronic complication associated with extremely preterm birth. Although BPD is now an uncommon condition in infants born with birthweights higher than 1,500 g, among infants born at or near the current limits of viability, BPD rates have not improved over the past 2 to 3 decades and may be increasing. No single therapeutic intervention is effective at preventing BPD. As such, clinicians must use multiple evidence-based strategies to help reduce BPD rates. This review examines current evidence-based approaches to BPD prevention, primarily focusing on data obtained from randomized controlled trials.